血浆D-二聚体和血气分析测定在肺栓塞中的临床价值  

Application of detection of plasma D-dimer level and blood gas analysis in patient with pulmonary embolism

作　　者：仇爱民[1] 陶章[1] 祁风亮 张海林[1] 张建生[1] 

机构地区：[1]盐城市第三人民医院呼吸内科,江苏盐城224001

出　　处：《临床肺科杂志》2015年第3期518-520,共3页Journal of Clinical Pulmonary Medicine

摘　　要：目的回顾急性肺栓塞时动脉血气指标Pa O2和血浆D-二聚体的变化,探讨动脉血气指标Pa O2联合血浆D-二聚体测定对急性肺栓塞诊断价值。方法回顾性分析14例急性肺栓塞患者的性别、年龄、高危因素、临床表现,与对照组对照血浆D-二聚体值、动脉血气分析测定结果。结果临床表现为胸痛8例,咯血4例,血压降低3例,咳嗽12例,心悸3例,紫绀2例,单侧下肢水肿2例。肺栓塞组血浆中D-二聚体明显高于对照组,动脉血气分析Pa O2明显低于对照组。肺栓塞组患者中血浆D-二聚体和Pa O2分别检测与血浆D-二聚体和Pa O2联合检测的灵敏度比较,联合检测的灵敏度明显增高。结论血浆D-二聚体和Pa O2联合检测可以提高肺栓塞诊断的灵敏度,对肺栓塞的诊断和有重要意义。Objective To investigate the application value of detection of plasma D-dimer level and blood gas analysis in patient with pulmonary embolism in order to provide reference for clinical diagnosis and treatment. Methods The clinical data of 14 patients with pulmonary embolism were reviewed to analyze their age, gender, high-risk and clinic symptoms. Plasma D-dimer level and blood gas analysis were contrasted between the pulmonary embolism group and the control group. Results The clinical manifestations of 14 pulmonary embolism patients in-cluded chest pains （8 cases）, hemoptysis （4 cases）, cough （4 cases）, heart palpitations （3 cases）, cyanosis （2 cases）, oedema leg （2 cases） and lower blood pressure. The plasma level of D-dimer was obviously higher in the pulmonary embolism group than in the control group, and the level of PaO2 was significantly lower in the pulmonary embolism group than in the control group （P〈0. 05）. Conclusion The combined detection of plasma D-dimer and blood gas analysis has a high sensitivity in the diagnosis of patients with pulmonary embolism.

关 键 词：肺栓塞 血气分析 D-二聚体 

分 类 号：R563.5[医药卫生—呼吸系统]