普氏蹄蝠下丘CF-CF联合敏感神经元的声反应  

Response Properties of CF-CF Combination Sensitive Neurons in Inferior Colliculus of Pratt's Roundleaf Bat

作　　者：邹丽芳[1] 李琳[1] 危晨雪 唐佳[1] 

机构地区：[1]华中师范大学生命科学学院遗传调控与整合生物学湖北省重点实验室,武汉430079

出　　处：《动物学杂志》2015年第1期9-15,共7页Chinese Journal of Zoology

基　　金：国家自然科学基金项目(No.31000959)

摘　　要：为了研究普氏蹄蝠(Hipposideros pratti)下丘(IC)中恒频-恒频(CF-CF)联合敏感神经元声反应特性,以及易化型和抑制型CF-CF联合敏感神经元在IC高频表征区神经元中所占的比例,实验记录了普氏蹄蝠IC神经元在不同频率和声强下的单声反应以及在不同延迟下的双声反应。本实验采用在体细胞内电生理技术从7只听力正常的蝙蝠上共获得77个IC声敏感神经元。所获得的数据经过处理并应用Sigma Plot 10.0软件作图。研究结果显示,77个神经元中37(48.1%)个为CF-CF联合敏感神经元,且多数为抑制型(24/37),少数为(13/37)易化型。实验结果说明普氏蹄蝠IC中既存在易化型也存在抑制型CF-CF联合敏感神经元,其中抑制型CF-CF联合敏感神经元比易化型所占比例更高。这些CF-CF联合敏感神经元有助于蝙蝠在巡航过程中处理回声信息时进行频谱和时相的整合。To study the response properties of constant frequency-constant frequency （CF-CF） combination sensitive neurons in inferior colliculus （IC） of pratt＇s roundleaf bat （Hipposideros pratti）, and the proportions of facilitatory and inhibitory CF-CF combination sensitive neurons in high frequency representation region of IC, single CF tones with different frequencies and intensities and double CF tones with different interpulse intervals were used to study the responses of combination sensitive neurons in IC. The responses of 77 IC neurons of 7 bats with normal hearing were recorded by intracellular recordingmethod. All data obtained under different stimulation conditions were processed and plotted using Sigmaplot 10.0. Among 77 recorded neurons, 37 （48.1%） were the CF-CF combination sensitive neurons. Most neurons （24/37） were the inhibitory CF-CF combination sensitive neurons （Fig. 2B） and the remaining 13 were the facilitatory ones （Fig. 2A）. These results indicate that there are both facilitatory and inhibitory CF-CF combination sensitive neurons in IC of pratt＇s roundleaf bat. And the proportion of inhibitory CF-CF combination sensitive neurons was higher than that of facilitatory ones. The CF-CF combination sensitive neurons may play an important role in temporal and spectral integration of information in the echoes from the targets during the navigation of bats.

关 键 词：CF-CF联合敏感神经元 易化 抑制 下丘 普氏蹄蝠 

分 类 号：Q42[生物学—神经生物学]