甘露聚糖肽胶囊治疗慢性咽炎的疗效观察  

Efficacy Observation of Mannatide in Treating Chronic Pharyngitis

作　　者：杨登权 张小平[1] 

机构地区：[1]四川省宜宾市第二人民医院耳鼻喉科,宜宾644000

出　　处：《中国医药导刊》2015年第1期71-72,共2页Chinese Journal of Medicinal Guide

摘　　要：目的：观察甘露聚糖肽胶囊治疗慢性咽炎的临床效果。方法：选择笔者所在医院2007年2月~2012年12月期间收治的慢性咽炎患者90例,随机分为治疗组和对照组,各45例,两组均给予常规治疗,同时对照组加服匹多莫德胶囊,治疗组加服甘露聚糖肽胶囊。结果：治疗组临床总有效率为91.11%,约高于对照组的84.44%,但两组总有效率比较差异无统计学意义（P〉0.05）。但治疗组T淋巴细胞亚群CD3＋、CD4＋、CD4＋/CD8＋值较对照组显著提高（P〈0.01）,平均发作持续间、感染复发次数较对照组显著降低（P〈0.05）。结论：甘露聚糖肽通过提高慢性咽炎患者免疫功能,能显著降低患者反复发作次数,缩短复发感染持续时间。Objective： To observe the clinical efficacy of mannatide to treat chronic pharyngitis.Methods：90 chronic pharyngitis patients choosen from the hospital where the author served in from the period during February 2007 to December 2012 were randomly divided into treatment group and control group,45 patients respectively. On the basis of conventional treatment,the control group was applied pidotimod Capsules and the treatment group was applied mannatide capsules, Results：The total effective rate of treatment group was 91.11% which was higher than the control group of 84.44%, but the total effective rate had no significant difference （P：〉0.05）.The T lymphocyte subsets,CD3＋, CD4＋, CD4＋/CD8＋ values was significantly increased,compared to the control group （P〈0.01） and the average lasting time,infection relapse frequency of treatment group was significantly lower than the control group （P〈0.05）.Conelusion： Mannatide can significantly reduce the number of patients with recurrent, shorten the duration of recurrent infection by enhancing the patients＇ immune function.

关 键 词：甘露聚糖肽 慢性咽炎 免疫 

分 类 号：R766.14[医药卫生—耳鼻咽喉科]