海马补肾壮阳丸治疗特发性弱精子症  

Therapeutic Effect of Haima Bushen Zhuangyang Pill on Idiopathic Asthenospermia

作　　者：陈建设[1] 周东[1] 孙自学[1] 门波[1] 张金锋[1] 

机构地区：[1]河南省中医院,郑州450002

出　　处：《中国实验方剂学杂志》2015年第4期186-188,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：河南省中医药科学研究专项(2013ZY02005);河南省郑州市金水区科技攻关计划项目(金科[2011]31号-54);郑州市科技创新团队项目(121PCXTD522)

摘　　要：目的:观察海马补肾壮阳丸对特发性弱精子症精子浓度、活动率及直线运动速度的影响。方法:采用SAS 8.0系统随机化程序,将140例特发性弱精子症患者随机分为试验组和对照组,最终128例纳入统计分析,其中试验组66例,对照组62例。试验组采用自制中成药"海马补肾壮阳丸"治疗,对照组采用右归丸治疗,疗程为60 d。结果:试验组总有效率86.36%,优于对照组(P<0.05)。治疗后试验组前向运动精子密度为(18.60±10.45)×106/m L,前向运动精子活动率为(33.78±16.22)%,总精子活动率为(50.43±19.93)%,精子直线运动速度为(46.88±15.93)μm·s-1,均优于对照组(P<0.05)。结论:海马补肾壮阳丸能改善特发性弱精子症主要临床指标,具有较好的疗效,为临床提供了有效方剂。Objective： To observe the therapeutic effect of Haima Bushen Zhuangyang pill on sperm concentration, activity ratio and linear velocity of idiopathic asthenospermia. Method： One hundred and forty patients were divided into the control group and the treatment group according to SAS 8.0 randomization procedure. Finally, 66 patients in the treatment group and 62 patients in the control group were enrolled. The patients in the treatment received self-made Chinese medicine of Haima Bushen Zhuangyang pill and the patients in the control group received Yougui pill. All patients received 60 days of treatment. Result ： The total efficiency of the treatment group was 86.36% , which was better than that of the control group （P 〈 0.05）. After treatment, concentration of forward movement sperm was （18.60±10.45）× 10^6/mL, activity ratio was （33.78±16.22）% , total activity rate of sperm was （50.43±19.93） % , and linear velocity was （46.88±15.93 ）μm·s^-1 in the treatment group, which was better than the control group （P 〈 0.05）. Conclusion： Haima Bushen Zhuangyang pill could improve the main clinical indicators of idiopathic asthenospermia effectively.

关 键 词：海马补肾壮阳丸 特发性弱精子症 临床疗效 

分 类 号：R287.6[医药卫生—中药学]