改良小剂量骨水泥椎体成形术治疗中老年胸腰椎病理性骨折150例  

Modified method of small dose of bone cement percutaneous vertebroplasty in treatment of pathological fracture of thoracolumbar among middleaged and elderly people in 150 cases

作　　者：郜顺兴[1] 王芳芳[1] 田伟荣[1] 杨中华[1] 陈彦平[1] 陶晓冰[1] 褚定坤[1] 

机构地区：[1]河北省沧州中西医结合医院,河北沧州061001

出　　处：《中国医药导报》2015年第3期33-36,共4页China Medical Herald

基　　金：河北省沧州市科学技术研究与发展指导计划课题(编号1123054ZD)

摘　　要：目的探讨改良小剂量骨水泥椎体成形术（PVP）方法治疗中老年胸腰椎病理性骨折的临床效果及安全性。方法选择2012年10月～2013年10月在沧州中西医结合医院住院治疗中老年胸腰椎病理性骨折患者300例,随机分为两组。治疗组150例,采用改良小剂量骨水泥PVP方法;对照组150例,采用传统PVP手术方法。观察两组患者治疗前后疼痛视觉类比评分（VAS）、术中骨水泥使用量、手术时间、器械花费等情况。结果两组患者PVP技术操作成功率均为100%。治疗组每节椎体平均手术时间为（22.23±3.57）min,对照组为（41.25±4.32）min,两组比较差异有统计学意义（P〈0.05）;治疗组每节椎体注入骨水泥（2.45±0.32）m L,对照组为（4.17±0.57）m L,两组比较差异有统计学意义（P〈0.05）;术后第3天,治疗组VAS评分为（2.47±0.51）分,对照组为（2.51±0.48）分,两组比较差异无统计学意义（P〉0.05）。结论改良小剂量骨水泥PVP治疗方案不仅可以有效缓解患者临床症状,减少PVP相关并发症的发生,同时缩短了手术操作时间,简化了手术操作步骤,节约治疗费用,是治疗中老年胸腰椎病理性骨折安全、有效、可行、值得推广的方法。Objective To investigate the clinical efficacy, and safety of modified method of small dose of bone cement percutaneous vertebroplasty treated pathological fracture of thoracolumbar among middle-aged and elderly. Methods From October 2012 to October 2013, in Hebei Province Cangzhou Hospital of Integrated Traditional and Western Medicine, 300 patients with thoracolumbar pathological fracture were randomly divided into two groups. Treatment group（150 cases） was given the improved small doses of bone cement PVP method; the control group（150 cases） was given traditional PVP operation method. The pain visual analog scale（VAS） before and after treatment and bone cement usage, operation time, equipment cost of two groups were observed and compared. Results PVP technical operation success rate of two groups was 100%. Treatment group each vertebral body average operation time was（22.23 ±3.57） min,the control group was（41.25±4.32） min, the difference was statistically significant（P 〈0.05）; injected bone cement of each section in treatment group was（2.45±0.32） m L, the control group was（4.17±0.57） m L, the difference was statistically significant（P 〈0.05）. After operation 3 days, VAS score of the treatment group was（2.47 ±0.51） scores, the control group was（2.51 ±0.48） scores, the difference was not statistically significant（P〉0.05）. Conclusion Modified method of small dose of bone cement PVP technology not only can effectively relieve the clinical symptoms, reduce the PVP related complications, but also can shorten the operation time, simplify the operation steps, save the cost of treatment. It is a method of safe, effective, feasible and worth extending in the treatment of thoracolumbar pathological fracture among middle-aged and elderly people.

关 键 词：经皮椎体成形术 骨水泥 技术改良 

分 类 号：R687.3[医药卫生—骨科学]