原发性干燥综合征合并甲状腺疾病的临床及实验室检查特点  

Clinical Features and Laboratory Examination Results of Primary Sjogren Syndrome Complicated with Thyroid Disorders

作　　者：吴际[1] 谢波[2] 

机构地区：[1]广东省人民医院/广东省医学科学院检验科,广东广州510080 [2]湖北省武汉市第一医院检验科,湖北武汉430022

出　　处：《临床医学工程》2014年第12期1559-1560,共2页Clinical Medicine & Engineering

摘　　要：目的探讨原发性干燥综合征(p SS)合并甲状腺疾病的临床及实验室检查特征。方法选取44例p SS合并甲状腺疾病患者作为观察组,45例单纯p SS患者作为对照组,比较两组患者的临床表现和实验室检查结果。结果与对照组相比,观察组患者易出现睡眠差和疲倦,其FT4低于对照组,TSH、Tg Ab、TPO、LDH、AST及ESR均高于对照组。结论自身抗体联合检测阳性的p SS患者,应常规检测甲状腺功能、Tg Ab、TPO、肝功和ESR等指标,以及时确认是否合并甲状腺功能异常。Objective To explore the clinical features and laboratory examination results of primary Sjogren syndrome （pSS） complicated with thyroid disorders. Methods 44 cases of patients with pSS complicated with thyroid disorders were selected as observation group, 45 cases of patients with simple pSS were selected as control group. The clinical features and test results were observed and compared. Results Compared with control group, patients in observation were easier to appear poor sleep and fatigue （P 〈0.05）. The FT4 of the observation group was lower than that of the control group, the TSH, TgAb, TPO, LDH, AST and ESR values of the observation group were higher than those of the control group. Conclusions Specific detection of thyroid and liver fimction, TgAb, TPO and ESR are recommended to patients with positive results for determination ofautoantibodies to confirm the presence of thyroid disorders.

关 键 词：原发性干燥综合征 甲状腺疾病 临床表现 实验室检查 

分 类 号：R593[医药卫生—内科学] R581[医药卫生—临床医学]