复方双层缓释药膜的制备与临床应用研究  

The Preparation and Clinical Application study of Cow Bezoar and Borneol Mixture Double Releasing-control Membranes

作　　者：赵呈利[1] 孙迎东[1] 荣丽[1] 孙继军[1] 

机构地区：[1]滨州医学院附属医院,山东滨州256603

出　　处：《中国医学创新》2014年第31期24-26,共3页Medical Innovation of China

摘　　要：目的:对复方双层缓释药膜的制备及治疗复发性口腔溃疡的疗效观察分析。方法:复方双层缓释药膜制备、应用于复发性口腔溃疡病例。结果:复方双层缓释药膜为黄色半透明薄膜,有一定的韧性,具有明显的冰片及人工牛黄的清香气;复方双层缓释药膜、养阴生肌散组,总有效率分别达98%、84%,尤以复方双层缓释药膜临床效果良好,两组对比差异有统计学意义(P<0.05),且均显著优于对照组(P<0.01)。结论:该膜制备工艺简单,止痛迅速,对缩短溃疡期,促进愈合,提高临床治疗疗效非常确切,具有可行的临床应用推广价值。Objective：To prepare the Cow bezoar and Borneol mixture double releasing-control membranes and observe the effect on recurrent oral ulcer（ROU）patients. Method：The Cow bezoar and Borneolmixture double releasing-control membranes were used to ROU（patients）. Result：The effective rates of the Cow bezoar and Borneol mixture double releasing-control membranes and the Mixed powder for raise and promote tissue regeneration group were 98%and 84%separately. Both groups were better than the control group（P〈0.01）. The Cow bezoar and Borneol mixture double releasing-control membranes were especially efficacious（P〈0.05）. Conclusion：The cow-bezoar and borneol mixture double releasing-control membranes can stop pain quickly and shorten the period of ulcer. It can raise the effect of clinical treatment and possess the values of popularization.

关 键 词：复方双层缓释药膜 制备 治疗 复发性口腔溃疡 

分 类 号：R944[医药卫生—药剂学]