头皮发际区微针疗法对血管性痴呆患者认知功能及内皮素的影响  

Effect on the Cognitive Ability and ET of Patients with Vascular Dementia Treated by Micro- acupuncture in the Hairline Regions of the Scalp

作　　者：牛文民[1] 刘智斌[1] 杨晓航[1] 王渊[1] 

机构地区：[1]陕西中医学院第一附属医院,陕西咸阳712083

出　　处：《中医药信息》2015年第1期73-75,共3页Information on Traditional Chinese Medicine

基　　金：陕西省科技厅项目(No.2010K15-01)

摘　　要：目的:探讨头皮发际区微针疗法治疗血管性痴呆(VD)的疗效。方法:60例VD患者随机分为两组。其中观测组用头皮发际区微针疗法,对照组用口服药物疗法。方法:采用放射免疫法捡测血浆内皮素(ET)的浓度,采用MMSE和ADL量表评定患者的认知功能、社会活动功能及日常生活能力。结果:两组疗效比较,观测组的总有效率为60.00%,对照组的总有效率为53.33%,二者差异有统计学意义(P<0.05);治疗后两组MMSE、ADL量表评分与治疗前自身比较均有显著改善(P<0.01);治疗后,观测组的MMSE、ADL量表评分与对照组相比较改善更为明显(P<0.05);两组血浆ET水平治疗后较治疗前自身比较均有显著下降(P<0.01);治疗后,观测组血浆ET水平与对照组比较,下降更为明显(P<0.05)。结论:头皮发际区微针疗法对于VD患者具有确切疗效,其治疗机理与降低血浆ET含量相关。Objective ： To evaluate the efficacy of patients with vascular dementia （. V Lt） treateo Dy micro - acu- puncture in the hairline regions of the scalp. Methods ：60 cases with VD were treated by micro - acupuncture in the hairline regions of the scalp. Before and after treatment, the changes about Endothelin （ET）, MMSE and ADL rating scale were examined for evaluating patients＇ cognitive function and activities of daily living. Results： The effective rate in the observed group （60. 00% ） was higher than that in the control group （53.33%） （P 〈 0.05 ） ;After treatment ,the MMSE and ADL scores in two groups improved significantly（ P 〈 0.01 ） ; the MMSE and ADL scores in the observed group improved better than that in the control group（P 〈 0.05 ）. After treatment , the ET levels in two groups decreased significantly（ P 〈 0.01 ） ; the ET levels in the observed group decreased more than that in the control group （ P 〈 0.05 ）. Conclusion ： The micro - acupunc- ture in the hairline regions of the scalp is an effective therapy for VD and its therapeutic mechanism may be closely related to reducing ET levels in blood.

关 键 词：血管性痴呆 头皮发际区微针疗法 内皮素 

分 类 号：R246.6[医药卫生—针灸推拿学]