散射体和吸收体的超声调制光学成像  

Imaging by Optically Scattering Objects and Absorption Objects with Ultrasound-Modulated Optical Tomography

作　　者：朱莉莉[1] 李晖[1] 

机构地区：[1]福建师范大学光电与信息工程学院医学光电科学与技术教育部重点实验室,福建省光子技术重点实验室,福建福州350007

出　　处：《中国激光》2015年第2期124-129,共6页Chinese Journal of Lasers

基　　金：国家自然科学基金(61178089);福建省科技计划重点项目(2011Y0019);福建省教育厅科技项目(JA13074)

摘　　要：具有超声定位的高空间分辨率特点和光学检测的高灵敏度特点的超声调制光学成像(UOT)既可以对光吸收介质进行成像也可以对光散射介质进行成像。在介质和光电倍增管(PMT)之间放置两个小孔,通过控制PMT的探测位置提高了系统的信噪比和成像对比度,同时获得了浑浊介质中隐含散射体和吸收体的一维成像。实验结果表明在不同的探测位置处,超声调制光信号的调制深度M与介质的吸收系数和散射系数的关系不同。选择合适的PMT探测位置,超声调制光学成像信号不仅可以体现吸收体和散射体的大小和强弱,还可以分辨出吸收体和散射体的不同。Ultrasound-modulated optical tomography （UOT） has high spatial resolution of ultrasonic location and high sensitivity of optical detection. Both of scattering objects and absorption objects can be imaged by UOT. The signal to noise ratio and image contrast of UOT is improved by laying two apertures between the sample and the detector （photomultiplier tube, PMT） and choosing appropriate position of PMT. One dimensional imaging of scattering objects and absorption objects buried in turbid media is provided. The experimental results indicate that the relationship between modulation depth of ultrasound-modulated signal and the scattering and absorption properties of media is dependent on detection position of PMT, The scattering objects and absorption objects are imaged simultaneously and distinguishable when PMT is at an appropriate position.

关 键 词：生物光学 光学成像 超声调制 吸收体 散射体 

分 类 号：O433.4[机械工程—光学工程] O426.3[理学—光学]