11268名健康体检人群甲状腺结节发生的流行状况调查分析  

Survey of prevalence of thyroid nodule in 11268 people receiving health examination

作　　者：徐厚兰[1] 危静[1] 兰满[2] 刘民杰[1] 将瑜 

机构地区：[1]杭州师范大学附属医院,浙江杭州310015 [2]浙江医院,浙江杭州310013

出　　处：《疾病监测》2014年第12期987-991,共5页Disease Surveillance

摘　　要：目的调查健康人群甲状腺结节发生的流行状况,分析影响甲状腺结节的危险因素。方法选择2012年5月至2013年5月杭州市区11 268名20岁以上人群的体检资料,并通过问卷调查,了解研究对象的职业、文化程度、家庭收入、生活习惯及压力状况等。依据甲状腺B超结果,统计研究人群甲状腺结节的患病率;采用t检验比较分析甲状腺结节组与非结节组各项体检指标的差异;采用logistic回归分析探究甲状腺结节的影响因素。结果研究对象中甲状腺结节患病率为37.19%,女性高于男性,差异有统计学意义;不同特征人群甲状腺结节的患病率有所不同,文化程度高者因工作压力大,甲状腺结节的患病率高。与非甲状腺结节组相比,甲状腺结节组的BMI、血压、血糖、总胆固醇及甘油三酯水平明显增高,差异有统计学意义(P<0.05)。logistic回归分析显示女性、年龄增长、肥胖、高血压、高血脂、糖尿病、吸烟可能是甲状腺结节的危险因素。结论健康人群甲状腺结节的患病率较高,女性的患病率明显高于男性。年龄增长、肥胖、高血压、高血脂、糖尿病、吸烟是甲状腺结节的危险因素,高学历者患甲状腺结节的风险增大。Objective To understand the prevalence of thyroid nodule in healthy population and risk factors related to thyroid nodule prevalence. Methods A total of 11 268 people receiving health examination m Chengbei district of Hangzhou from May 2012 to May 2013 were included in this survey. A questionnaire survey was conducted among these people to collect the information about their occupation, education level, household income, lifestyle and mental stress. According to the results of thyroid type B ultrasonic detection, the prevalence of thyroid nodule was calculated. The differences in health examination results between thyroid nodule group and non-thyroid nodule group were compared with t test. Logistic regression analysis was conducted to identify the risk factors related to the prevalence of thyroid nodule. Results The prevalence of thyroid nodule in this population was 37. 19%, the prevalence was higher in females than in males. The difference was statistically significant. The prevalence of thyroid nodule was higher in people with high education level and high mental stress. Compared with non-thyroid nodule group, the BMI, blood pressure, blood sugar level, total cholesterol level and triglyceride level were significantly higher in thyroid nodule group, the difference was statistical significant. Logistic regression analysis indicated that female, age, obesity, hypertension, hypeflipidemia, diabetes and smoking might be related factors to thyroid nodule. Conclusion The prevalence of thyroid nodule in healthy people is high. The prevalence is significantly higher in females than in males. Age, obesity, hypertension, hyperlipidemia, diabetes, smoking, may be the related factors to thyroid nodules. People with high education level were at higher risk.

关 键 词：甲状腺结节 流行状况 危险因素 

分 类 号：R581[医药卫生—内分泌]