冠心病心绞痛合并糖尿病气虚证危险因素分析  

Analysis of Risk Factors on Angina Pectoris in Coronary Heart Disease Combining with Diabetes Mellitus in Qi Deficiency Pattern

作　　者：徐学功 张军鹏 史琦[2] 陈建新[3] 徐变玲 张理 程雪[4] 王伟伟[4] 赵慧辉[3] 王伟[3] 

机构地区：[1]河南省郑州市中医院心病科,郑州450000 [2]中日友好医院中医科,北京100029 [3]北京中医药大学基础医学院,北京100029 [4]河南中医学院,硕士研究生2012级郑州450000

出　　处：《中国中医药现代远程教育》2014年第24期14-17,共4页Chinese Medicine Modern Distance Education of China

基　　金：北京中医药大学自主选题[No:2009JYBZZ-XS014];河南省郑州市科技创新领军人才项目[No:N2012SC1280]

摘　　要：目的探讨冠心病心绞痛合并糖尿病气虚证的主要危险因素,为冠心病心绞痛合并糖尿病气虚证＂理化指标——对应平台＂预警系统提供临床依据。方法在流行病学调查基础上,得到100例符合冠心病心绞痛合并糖尿病的病例,分为气虚证组、非气虚证组,运用单因素、多因素非条件Logistic回归方法分析气虚证的相关危险因素。结果多因素非条件Logistic回归结果表明,左室射血分数[β值为0.156,OR（95%CI）为1.169（1.009-1.354）]、餐后2 h血糖[β值为0.086,OR（95%CI）为1.090（1.006-1.180）]、三酰甘油[β值为1.190,OR（95%CI）为3.288（1.054-10.259）],与冠心病心绞痛合并糖尿病患者的气虚证呈负相关。结论冠心病心绞痛合并糖尿病气虚证与左室射血分数、餐后2 h血糖、三酰甘油等关系密切,且均呈负相关。临床上应尽早给予干预措施以预防疾病的发生及恶化。Objective To explore the main risk factors of angina pectoris in coronary heart disease（ CHD） combining with diabetes mellitus（ DM） in qi deficiency pattern and provide clinical basis for pre-warning system of physicochemical indexes corresponding platforms for patients with angina pectoris in CHD combining with DM in qi deficiency pattern. Methods On the basis of epidemiological investigations, 100 cases meeting the criteria of angina pectoris in CHD combining with DM were selected and divided into qi deficiency pattern group and non-qi deficiency pattern group. Related risk factors of qi deficiency pattern were analyzed by single or multi-factor unconditioned Logistic regression. Results Multi-factor unconditioned Logistic regression indicated that left ventricular ejection fraction（LVEF）（β=0.156; OR=1.169, 95%CI： 1.009-1.354）, 2h postprandial blood glucose（PBG）（β=0.086; OR=1.090, 95%CI： 1.006-1.180）, and triglyceride（β=1.190; OR=3.288, 95%CI： 1.054-10.259） were in negative correlations with patients with angina pectoris in CHD combining with DM in qi deficiency pattern. Conclusion Angina pectoris in CHD combining with DM in qi deficiency pattern is closely related with LVEF, 2h PBG, and triglyceride, and are all in negative correlations. In order to prevent the occurrence and deterioration of the disease, intervention measures should be provided as early as possible in clinic.

关 键 词：冠心病心绞痛合并糖尿病 气虚证 危险因素 LOGISTIC回归分析 

分 类 号：R259[医药卫生—中西医结合]