干预前后妇产科Ⅱ类切口手术围手术期预防应用抗菌药合理性分析  

Rationality Analysis of Prophylactic Application of Antibiotics during Perioperative Period in Patients with Type Ⅱ Incision Operation in Gynecology and Obstetrics before and after Intervention

作　　者：胡燕平[1] 章媛[1] 钱红燕[2] 

机构地区：[1]杭州市萧山区第三人民医院药剂科,杭州311251 [2]浙江萧山医院妇产科

出　　处：《中国药师》2015年第2期258-260,共3页China Pharmacist

摘　　要：目的：探讨干预前后我院妇产科Ⅱ类切口手术围手术期预防应用抗菌药的合理性,评价干预措施成效。方法：分别收集2012年4月~2013年3月（干预前）及2013年4月~2014年3月（干预后）我院妇产科Ⅱ类切口手术围手术期预防应用抗菌药患者的病历,对照组（干预前）共274份病历,干预组（干预后）321份,比较干预前后围手术期预防应用抗菌药合理性。结果：与对照组比较,干预组平均用药时间、平均住院时间、平均抗菌药费用均明显降低（P〈0.05）,两组的药品不良反应及手术切口感染率差异均无统计学意义（P〉0.05）。与对照组比较,干预组＂抗菌药选择不合理、无指征联合使用、用药时机不合理、术后用药时间过长、抗菌药用法用量不当和溶媒选择不当＂发生率均明显降低（P〈0.05）。结论：在实施管理干预措施后,我院妇产科围手术期预防应用抗菌药合理性明显提高。Objective： To investigate the rationality of prophylactic antibiotics application during perioperative period in the patients with type Ⅱ incision operation in gynecology and obstetrics in our hospital after the intervention. Methods： Totally 274 medical records of obstetrics and gynecology patients with type Ⅱ incision operation in our hospital from April 2012 to March 2013 were collected as the control group,another 321 medical records of obstetrics and gynecology patients with type Ⅱ incision operation in our hospital from April 2013 to March 2014 were collected as the intervention group. The rationality of prophylactic antibiotics application before and after the intervention was compared. Results： Compared with those in the control group,the average administration time,the hospitalization time and the cost of antimicrobial agents were significantly decreased in the intervention group（ P 0. 05）. The incidence of adverse drug reactions and operation incision infection between the two groups was not significant difference（ P 0. 05）. Compared with those in the control group,the incidence of irrational choice of antibacterial drugs,the combined use without indication,irrational medication time,over-time use,inappropriate use and improper choice of solvents in the intervention group was significantly reduced（ P 0. 05）. Conclusion： After the intervention,the rationality of prophylactic antibiotics application during perioperative period in the patients with type Ⅱ incision operation in gynecology and obstetrics in our hospital is improved significantly.

关 键 词：抗菌药 妇产科 Ⅱ类切口手术 预防 干预 

分 类 号：R978.1[医药卫生—药品]