地屈孕酮治疗早发型重度子痫前期的临床研究  

Clinical study of dydrogesterone in the treatment of early onset severe preeclampsia

作　　者：罗雪莹[1] 王玉荣[1] 

机构地区：[1]沈阳市第一人民医院妇产科,辽宁沈阳110041

出　　处：《中国医学工程》2014年第12期22-22,24,共2页China Medical Engineering

摘　　要：目的探讨地屈孕酮在早发型重度子痫前期治疗中的临床疗效。方法选取40例早发型重度子痫前期患者,随机分为对照组20例(采用镇静、硫酸镁解痉及降压等常规治疗),观察组20例(在常规治疗基础上口服地屈孕酮)。比较两组监测及治疗情况,并随访妊娠结局。结果经治疗后观察组孕妇的自觉症状、血压、尿蛋白、水肿、低蛋白血症较对照组有明显改善,且妊娠周数延长,新生儿平均体重及存活率提高。两组比较差异有统计学意义(P<0.05)。结论地屈孕酮辅助治疗早发型重度子痫前期能够明显改善妊娠结局,具有临床应用价值。[ Objective ] To explore Dydrogesterone auxiliary treatment the clinical effect of early-onset severe preeclampsla. [ Methods ] Selected 40 patients with early-onset severe preeclampisa,20 cases were randomly divided into control group （the calm,magnesium sulfate spasmolysis,step-down routine therapy ete）,observation group 20 cases （on the basis of conventional treatment of oral Dydrogesterone）,eompare two groups of monitoring and treatment,and follow-up the pregnancy outcome. [ Results ] Observation group of pregnant women after treatment self-conscious symptom,blood pressure,urine protein,the degree of edema and hypoalbuminemia obviously improved compared with control group,and extend gestational weeks,the average weight and improved survival.The more similar between the two groups have statistical significance（P〈0.05）. [ Conclusion ] Dydrogesterone auxiliary treatment early-onset severe preeclampisa can obviously improve the pregnancy outcome, have clinical application value.

关 键 词：地屈孕酮 早发型重度子痫前期 

分 类 号：R714.24[医药卫生—妇产科学]