EB病毒合并支原体肺炎患儿的临床特征及免疫功能  

Clinical features and immune function of children with EBV and mycoplasma pneumonia

作　　者：王德承[1] 张海 石慧萍[1] 石海艳[1] 李丹[1] 熊莉[1] 

机构地区：[1]湖北省黄石市妇幼保健院儿科,湖北黄石435000

出　　处：《实用临床医药杂志》2015年第1期92-94,共3页Journal of Clinical Medicine in Practice

基　　金：湖北省黄石市医药卫生科技攻关计划项目(黄科技发农[2012]1号)

摘　　要：目的探讨EB病毒(EBV)合并支原体肺炎(MP)患儿的临床特征及免疫功能。方法分析在本院接受治疗的34例MP合并EBV患儿的临床资料,并与同期进行治疗的37例单纯性支原体感染患儿及34例正常儿童比较,包括中性粒细胞降低、谷丙转氨酶(ALT)、肌酸激酶同工酶(CK-MB)、大叶实变、尿常规等及免疫功能改变。结果 3组儿童ALT异常、CKMB异常、大叶实变、尿常规异常的比例比较均有显著差异,以MP+EB组异常比例最高;3组儿童的CD4、CD8、CD4/CD8结果比较均有显著差异,以MP+EB组患儿CD4、CD4/CD8比例最低,而CD8比例最高。结论 EBV合并MP患儿肺部感染状况较严重,并发症也更多,并伴有免疫功能的紊乱。Objective To explore the clinical features and the immune function of children with EBV and mycoplasma pneumonia （MP）. Methods Clinical materials of 34 children with MP and EVB were analyzed retrospectively. The children with simple MP and normal children in the same period were selected as well. Decreased neutrophile granulocyte, glutamic-pyruvic transami- nase （ALT）, creatine kinase isoenzyme （CK-MB）, lobar consolidation, urinalysis and the changes of immune function in the three groups were compared. Results The differences in ALT, CK- MB, lobar consolidation and urinalysis in the three groups were significant, and changes of indexes mentioned above in MP ＋ EB group were significantly greater than those in the other two groups. The differences of CD_4, CD_8, CD_4/CD_8 in the three groups were significant, and the proportions of CD_4 and CD_4/CD_8 were the lowest and the proportion of CD_8 was the highest in the children with MP and EB. Conclusion The children with MP and EB are characterized by serious lung infec- tion, lots of complications and disorder of immune function.

关 键 词：EB病毒 支原体肺炎 免疫功能 

分 类 号：R563.1[医药卫生—呼吸系统]