谷胱甘肽在多壁碳纳米管-离子液体修饰碳糊电极上的间接电化学测定  

Indirect Electrochemical Analysis of Glutathione at Multi-walled Carbon Nanotubes and Ionic Liquids Composite Modified Carbon Paste Electrode

作　　者：黄娅婷[1] 黄颖[1] 

机构地区：[1]福建师范大学化学与化工学院,福建福州350007

出　　处：《分析科学学报》2015年第1期51-54,共4页Journal of Analytical Science

基　　金：福建省属高校科研专项基金(No.JK2010008)

摘　　要：制备了多壁碳纳米管一离子液体修饰碳糊电极（MWCNTs—ILs／CPE），并以对乙酰氨基酚（PA）为电催化媒介，研究了谷胱甘肽（GSH）在该修饰电极上的电化学行为。结果表明，GSH能明显增强PA在MwcNTs-ILs／CPE上的电化学响应，且示差脉冲伏安法（DPV）的氧化峰电流与其浓度在7．50×10^-7～1．OO×10^-4mol／L范围内呈良好线性关系，检测限（s／N-3）为1．65×10^-7mol／L。该方法简单、快速、灵敏，用于含GSH药物的测定，加标回收率为99．5％～101．8％。In this paper, a multi-walled carbon nanotubes and ionic liquids composite modified electrode （MWCNTs-ILs/CPE） was prepared and the assay performances of glutathione（GSH） in the presence of mediator（paracetamol, PA） at MWCNTs-ILs/CPE were evaluated. Results showed that GSH could increase the peak current of PA distinctly, and the catalytic peak current versus the concentration of GSH showed a good linear relationship over the range of 7.50 × 10 7-1.00× 10 ,4 mol/L with the detection limit of 1.65 ×10-7 mol/L（S/N = 3）. The proposed method was simple, rapid and sensitive, and has been successfully applied to the determination of GSH in Tathion Eye Drops sample with recovery of 99.5 %-101.8 %.

关 键 词：谷胱甘肽 多壁碳纳米管 离子液体 对乙酰氨基酚 电化学 

分 类 号：O657.1[理学—分析化学]