冠心病与糖代谢异常的关系  

Relationship between coronary heart disease and glucose metabolism disorder

作　　者：吕永成[1] 

机构地区：[1]广西钦州市第一人民医院心血管内科,广西钦州535099

出　　处：《心血管康复医学杂志》2015年第1期26-29,共4页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的：探讨冠心病与糖代谢异常的关系。方法：对本院心血管内科住院的512例冠心病患者进行糖耐量试验和冠脉造影检查，统计糖耐量异常患者比例，对比不同糖耐量患者之间的冠脉病变程度。结果：除已确诊为糖尿病的166例患者外，余下接受口服葡糖耐量试验（OGTT）的346例患者中，新发糖尿病74例（21.39％），糖调节异常152例 （43.93％）。512例冠心病患者中，糖尿病患者240例，高达46.88％。空腹血糖（FPG）与 OGTT 试验结果对比，单纯检测 FPG 糖尿病漏诊率为43.2％，糖调节异常漏诊率为73.7％；与糖耐量正常和糖耐量异常组比较，糖尿病组冠脉病变3支及以上病变比例明显升高（20.83％比30.92％比58.75％），P ＜0.05～＜0.01。结论：冠心病大多数合并有糖代谢异常，糖尿病组冠脉病变3支及以上病变比例明显高于糖耐量正常和糖耐量异常组；口服葡萄糖耐量试验能显著提高糖代谢异常的检出率。Objective：To explore the relationship between coronary heart disease （CHD）and glucose metabolism dis-order.Methods：A total of 512 CHD patients received glucose tolerance test and coronary angiography,the percent-age of patients with impaired glucose tolerance （IGT）was counted,and degree of coronary disease was compared a-mong patients with different glucose tolerance.Results：Besides the 166 patients already diagnosed as diabetes melli-tus （DM）,among the resting 346 patients undergoing oral glucose tolerance test （OGTT）,there were 74 cases （21.39%）of new-onset DM and 152 cases （43.93%）of impaired glucose regulation （IGR）.A total of 240 DM pa-tients occupied as high as 46.88% among the total 512 subjects.Compared with OGTT results,omission diagnose rate of DM was 43.2% and it′s 73.7% for IGR by single measuring fasting plasma glucose （FPG）;compared with normal glucose tolerance （NGT）and IGT group,there were more of ≥ 3 vessel coronary disease （20.83% vs. 30.92% vs.58.75%）in DM group,P 〈0.05~ 〈0.01.Conclusion：Most CHD patients complicate with glucose metabolism disorder.Percentage of patients with≥ 3 vessel coronary disease is significant rise in DM group than those of NGT and IGT group.OGTT can significantly raise detection rate of glucose metabolism disorder.

关 键 词：心血管疾病 糖尿病 葡糖耐量试验 葡萄糖代谢障碍 

分 类 号：R541.409[医药卫生—心血管疾病]