米索前列醇用于足月临产促宫颈成熟的效果观察  

Effect observation of misoprostol on cervical ripening in full-term parturient pregnant women

作　　者：梁领华 

机构地区：[1]广东省罗定市妇幼保健院产科,527200

出　　处：《国际医药卫生导报》2015年第4期552-554,共3页International Medicine and Health Guidance News

摘　　要：目的探讨米索前列醇用于足月临产促宫颈成熟的有效性及安全性。方法将126例足月临产孕妇按照数字表法随机分为两组，对照组（63例）孕妇给予静脉泵入小剂量催产素；观察组（63例）使用米索前列醇25ug放置阴道后穹隆促宫颈成熟计划分娩，并比较两组的效果。结果观察组孕妇促宫颈成熟总有效率（85．71％）显著高于对照组（65．08％）（P〈0．05），观察组产妇阴道分娩（74．60％）明显高于对照组（53．97％）（P〈0．05），而剖宫产则低于对照组（P〈0．05），观察组新生儿出生体重及新生儿窒息率与对照组比较差异无统计学意义（P〉0．05）。结论米索前列醇是一种阴道引产药物，方便、安全、可靠、经济、有效，成功率高，用于足月临产孕妇能有效促宫颈成熟的理想计划分娩方法。Objective To explore efficacy and safety of misoprostol on cervical ripening in full- term parturient pregnant women. Methods 126 full-term parturient pregnant women were randomly divided into control group and observation group according to random number table method, 63 cases in each group. Control group was given vein pump into small dose of oxytocin, while observation group was given misoprostol 25~tg placed in posterior fornix of vagina to promote cervical ripening. Compared the effect of two groups. Results The total effective rate of cervical ripening in observation group was significantly higher than that in control group （85.71% vs.65.08%, P〈0.05）; the rate of vaginal delivery in observation group was significantly higher than that in control group （74.60% vs.53.97%, P〈0.05）; there were no statistically significant differences in neonatal birth weight and the rate of neonatal asphyxia between two groups （P〉0.05）. Conclusion Misoprostol is a kind of vaginal abortion drug, is convenient, safe, reliable, economic, effective, with a high success rate, which is a ideal planned delivery method to promote cervical ripening in full-term parturient pregnant women.

关 键 词：孕产妇 足月临产 米索前列醇 促宫颈成熟 

分 类 号：R719.31[医药卫生—妇产科学]