乙肝相关性肾炎的临床特点及治疗  

Clinical Features and Treatment of HBV Associated Glomerulonephritis

作　　者：李辉兰 

机构地区：[1]青海省海西州德令哈市疾控中心,817000

出　　处：《中国继续医学教育》2015年第3期52-53,共2页China Continuing Medical Education

摘　　要：目的分析乙型肝炎病毒相关性肾炎的临床特点及治疗方法。方法将我院收治的50例乙肝相关性肾炎患者随机分为对照组和观察组,并观察分析临床特点及临床治疗效果。结果临床表现中肾病综合征最为常见,观察组肾病综合征患者10例,对照组7例。观察组MGN和MPGN分别占56%和30%,对照组分别占34%和36%;乙肝染色HBs Ag、HBe Ag的检出率观察组分别占52%和29.4%,对照组分别占50%和42%;治疗后有44例患者水肿消失,42例患者的尿蛋白减少。结论乙型肝炎病毒相关性肾炎多发于少儿,临床特点以肾组织中乙肝病毒抗原沉积以HBe Ag和HBs Ag为主,采用抗病毒结合保护肾脏功能治疗乙肝相关性肾炎的疗效较好。Objective To analyze the clinical features and treatment of hepatitis B virus associated glomerulonephritis.Methods In our hospital, 50 cases of hepatitis B associated glomerulonephritis patients were randomly divided into control group and observation group, and to observe and analyze the clinical characteristics and clinical outcomes.Results The clinical manifestations of nephrotic syndrome, the most common, 10 cases of nephrotic syndrome patients in the observation group, the control group had seven cases. Observer Group MGN and MPGN accounted for 56% and 30%, respectively, in the control group accounted for 34% and 36%, respectively, hepatitis B staining HBsAg, HBeAg detection rate in the observation group and 52% respectively 29.4% in the control group accounted for 50% and 42%, respectively, 44 patients after treatment edema disappeared, 42 cases of patients with urinary protein decreased. ConclusionHepatitis B virus associated glomerulonephritis mainly occur in children, the clinical features of hepatitis B virus in renal tissue deposition in HBeAg and HBsAg antigen-based, using anti-virus protection combined effect of renal function treatment of hepatitis B associated glomerulonephritis signiifcantly.

关 键 词：乙型肝炎病毒 临床特点 治疗 

分 类 号：R692.3[医药卫生—泌尿科学]