丙泊酚复合舒芬太尼用于人工流产术的麻醉  

The propofol combined with sufentanil as anesthetic for induced abortion

作　　者：金永俊[1] 

机构地区：[1]吉林省图们市人民医院麻醉科,吉林图们133100

出　　处：《转化医学电子杂志》2015年第1期61-62,共2页E-Journal of Translational Medicine

摘　　要：目的：研究人工流产手术中使用丙泊酚辅助舒芬太尼药剂来进行麻醉的功效，以及其对于机体的循环系统和呼吸状况的相关性．方法：择取60例拟准备进行人工流产手术的患者，与此同时病患之前没有出现类似禁忌征，ASA I ～II级，年龄18～35岁，体质量45～65 kg，孕期6～9周．将患者随机分为两个小组，使用丙泊酚辅助舒芬太尼麻醉的一组成为S 组，另一组P 组为使用丙泊酚的患者，每小组的患者各有30 例．S 组和P 组采用相同的手术方案，患者的体重、年龄和实施人工流产的时间都没有统计学差异性（P ＞0．05）．S 组舒芬太尼静脉推注0．10 μg／kg，静脉推注药剂丙泊酚的剂量是2 mg／kg，而对于P 组静脉推注药剂丙泊酚的量大小为2．5mg／kg．两组等待实施麻醉的效果良好之后再准备开始手术，与此同时仔细观察诱导之前、诱导后、手术结束时血压（Bp）、心率（HR）、血氧饱和度（SpO2 ）以及苏醒时间，并对麻醉效果进行分析评价．结果：S 组诱导和苏醒时间显著要比P 组更短（P ＜0．05）；诱导进行2 min 之后，P 组的Bp 降低、HR 缓慢，比起S 组SpO2 的减小要更加显著（P ＜0．05）；S 组麻醉效果明显优于P 组（P ＜0．05）．结论：在人工流产手术中采用丙泊酚辅助舒芬太尼麻醉的方式，麻醉的镇痛功效明显，使用的药物剂量比较少，并且起效更加迅速，呼吸、循环抑制较轻，患者术后苏醒快，此方法优于单纯用丙泊酚麻醉治疗者．AIM：To observe the propofol combined with sufen-tanil for anesthetic effect of induced abortion and the impact on the respiratory,circulatory system.METHODS：60 cases who underwent induced abortion without related taboos characteristics, with ASA physical status I -II grade,age 18 -35 years old, weight 45 -65 kg,6 -9 weeks of pregnancy,were randomly di-vided into two groups,S group and P group of propofol combined with sufentanil and propofol only,30 cases in each group.Both groups used the same surgical methods,and had no differences in age,weight and flow of time （P 〉0.05）.In S group sufentanil intravenous was injected 0.10 μg/kg,propofol bolus was dosed at 2 mg/kg,which in P group,propofol bolus was dosed at 2.5 mg/kg.Two groups were satisfied with anesthesia before induced a-bortion,and at the same time were observed before induction,af-ter induction,the end of surgery,blood pressure （Bp）,heart rate （HR）,oxygen saturation （SpO2 ）,wake time,and anesthet-ic effects were analyzed and evaluated.RESULTS：The induc-tion and emergence time of S group was significantly shorter than the P group （P 〈0.05）;Bp decreased 2 min after the induction of the P group,the HR slowed down,the SpO2 was lower than the S group （P 〈0.05）;anesthetic effect in S group was significantly superior in the P group （P 〈0.05 ）.CONCLUSION：The propofol combined with sufentanil for abortion, showed exact effect of narcotic analgesics,less medication,rapid onset,mild respiratory,circulatory inhibition,patients waking up faster.It is better than using only propofol phenol anesthesia treatment.

关 键 词：丙泊酚 舒芬太尼 人工流产术 麻醉 

分 类 号：R654.2[医药卫生—外科学]