老年皮肤病患者隐性梅毒感染的临床调查分析  

Clinical investigation and analysis of elderly patients with latent syphilis infection in Wuhan

作　　者：康小平[1] 薛芹[1] 张鹏[1] 龙飞 

机构地区：[1]武汉科技大学附属天佑医院皮肤科,武汉430064 [2]武汉市第七医院皮肤科,武汉430071

出　　处：《中国性科学》2015年第1期67-69,共3页Chinese Journal of Human Sexuality

基　　金：湖北省科技计划自然科学基金项目(2011CDB242)

摘　　要：目的:观察分析武汉地区老年皮肤病患者隐性梅毒感染情况。方法:入选对象为2011年1月至2013年12月武汉地区老年住院患者或者门诊体检者共1080例。受试者接受梅毒血清学检查,并且统计显性梅毒和隐性梅毒的年度检出情况,隐性梅毒的发病特点以及科室分布。结果:统计2011年到2013年梅毒检测结果,其中确诊为梅毒阳性的患者共112例,检出率为10.4%。其中隐性梅毒的检出率为65例,隐性梅毒检出率为58.0%;显性梅毒有47例,显性梅毒检出率为42.0%。显性梅毒和隐性梅毒的检出率对比有显著性的统计学差异。近3年梅毒感染的阳性率有上升的趋势,其中2012年显性梅毒的检出率对比2013年有明显下降,但隐性梅毒的检出率则有明显上升。隐性梅毒的发病特点是感染来源主要是来源密切接触者,占73.8%,对比显性梅毒的29.8%有显著统计学差异;发病中男性患者多于女性患者,隐性梅毒患者中有63.1%为男性患者,36.9%为女性患者;隐性梅毒患者中文化程度相对较低,中学或以下程度的有89.2%,这对比显性梅毒患者也有统计学差异。隐性梅毒患者中有72.3%患者自身具有基础疾病。妇科和体检科对隐性梅毒患者的检出率较高,分别是14.6%和12.5%,对比其他科室的隐性梅毒检出率对比有显著性统计学差异。结论:重视武汉地区老年隐性梅毒感染情况,提高对老年皮肤病患者隐性梅毒的筛查对抑制梅毒传播有重要意义。Objectives： To observe and analyze the latent syphilis infection condition of elderly patients in Wuhan. Methods： The 1,080 elderly inpatients or outpatients from January 2011 to December 2013 in Wuhan were selected as study subjects and received syphilis serology detection. The detection rates of dominant and latent syphilis were calculated,so as the characteristics and department distribution of latent syphilis. Results： According to the detection results from 2011 to 2013,there were a total of 112 patients were diagnosed as positive,a detection rate of 10. 4%,of which there were 65 cases of latent syphilis（ 58. 0%） and 47 cases of dominant syphilis（ 42. 0%）. There was statistically significant difference in the detection rate of dominant and latent syphilis. The incidence of latent syphilis is primarily characterized by close contact with patients,accounting for 73. 8%,compared to the 29. 8% for dominant syphilis,with a significant difference; incidence among male patients was higher than female patients,63. 1 % vs. 36. 9%; patients with latent syphilis had low educational level,the educational level of89. 2 % of whom was secondary or below,demonstrating statistically significant difference in comparing with that of dominant syphilis. 72. 3 % of latent syphilis patients had underlying disease. Gynecology and physical examination had detection rate for patients with latent syphilis,14. 6% and 12. 5 % respectively,with statistically significant differences compared to that of other departments. Conclusion： Attaching importance to the latent syphilis infection situation of elderly patients as well as enchased screening is very important in suppressing the spread of syphilis.

关 键 词：武汉 老年 隐性梅毒 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]