自体与同种异体组织移植重建膝关节前十字韧带  

Autologous and allogeneic tissue transplantation for reconstruction of the anterior cruciate ligament of the knee

作　　者：朱栩宏[1] 姜飞[1] 毛丰刚[1] 

机构地区：[1]阿克苏地区第一人民医院骨二科,新疆维吾尔自治区阿克苏市843000

出　　处：《中国组织工程研究》2014年第51期8325-8329,共5页Chinese Journal of Tissue Engineering Research

基　　金：阿克苏地区科技基金~~

摘　　要：背景:关节镜辅助下重建前十字韧带的移植物主要有自体组织移植物、同种异体组织移植物,各具优势,对于如何选择移植物存在较多争议。目的:评价关节镜辅助下自体与同种异体组织重建膝关节前十字韧带的疗效。方法:回顾性分析2010年6月至2013年6月于阿克苏地区第一人民医院骨科行关节镜辅助下膝关节十字韧带重建52例患者的临床资料,其中自体组织移植组27例,同种异体组织移植组25例。结果与结论:与同种异体组织移植组相比,自体组织移植组重建后住院天数和发热天数均减少(P<0.05)。两组重建后物理学检查、功能试验、国际膝关节文献编制委员会分级评估标准与Lysholm-Tegner膝关节综合功能评定结果比较差异无显著性意义(P>0.05)。结果证实,关节镜辅助下自体与同种异体组织重建膝关节前十字韧带均是安全可行的手术方案;自体组织移植与同种异体组织移植重建前十字韧带重建后膝关节功能恢复疗效相同,但两组间住院天数和发热天数之间的差异将影响人们对移植物的选择。BACKGROUND： There are two kinds of grafts used in anterior cruclata ligament reconstruction： autograft and allograff, each of which has its own advantages and disadvantages, There are a lot of debates on the selection of grafts. OBJECTIVE： To compare the clinical ouk;omes and differences of arthroscopic anterior cruciate ligament reconstruction using allografts and autografts, METHODS： Form June 2010 to June 2013, 52 patients with anterior ~ruclate ligament injuries were divided randomly into two groups： 27 patients received autografts and 25 patients underwent aUografts. RESULTS AND CONCLUSION; The average hospitalization day8 and postoperative fever days were fewer in the autograft group than the allograft group （P 〈0,05）, There was no significant difference between the two groups in terms of physical examination, functional tests, grading evaluat on and Lysholm-Tegner evaluat on （P 〉 0.05）. These findings indicate that both autografts and allografts for arthroscopic anterior cruciate ligament reconstruction are safe and feasible. There is no difference in functional recovery and autografta, but the their difference in hospitalization days and postoperative fever days can influence the choice of grafts.

关 键 词：组织工程 关节镜 膝关节 韧带 移植 组织构建 前十字韧带 损伤 自体组织 同种异体组织 重建后住院天数 重建后体温 重建后功能恢复 

分 类 号：R318[医药卫生—生物医学工程]