SPF级长爪沙鼠生长指标及血液学指标正常参考值的研究  

Study on Growth Index and Hematology Normal Reference Values of SPF Mongolian gerbils

作　　者：赵士海[1] 杨林[1] 代路路 刘盛来[1] 邝少松[1] 唐小江[1] 

机构地区：[1]广东省医学实验动物中心比较医学实验室,佛山528248

出　　处：《实验动物科学》2014年第6期21-25,共5页Laboratory Animal Science

基　　金：广东省科技计划项目-SPF级长爪沙鼠标准化封闭群的建立(No.2011B060300016)

摘　　要：目的建立SPF级雌、雄远交群长爪沙鼠血液学及生长指标的正常参考值,为长爪沙鼠的应用研究提供基础数据。方法对不同日龄及周龄的雌、雄长爪沙鼠体质量、血常规及血生化指标进行测定。结果实验得到长爪沙鼠在不同日龄的生长曲线,不同周龄不同性别长爪沙鼠血液生理生化指标及其正常参考范围。结论不同日龄长爪沙鼠的体质量增长速度不同,多数血液生理生化指标受年龄和性别的影响,因此,在应用长爪沙鼠进行研究、实验结果评价时,要充分考虑性别和年龄对实验动物血液生理及生化指标的影响。Objective Established normal reference range of hematology and growth indicators about male and female SPF outbred population Mongolian gerbils and provided a basic data for the using of Mongolia gerbils. Method The body weight, routine blood test and blood biochemical indices in different days and weeks of male and female Mongolian gerbils were measured. Result Mongolian gerbils growth curve in different ages, normal reference range of different sex gerbils physiological index value of blood in different days and ages were detected. Conclusion Difference ages takes greater impact on the growth of gerbils weight, most physiological and biochemical index of blood are affected by age and gender, so in scientific research the effects of gender and age on the animal blood physiology and biochemistry indicators should be fully considered, when the Mongolian gerbils are using in the science research.

关 键 词：SPF级长爪沙鼠 生长指数 血液生理 血液生化 

分 类 号：Q95-33[生物学—动物学]