温肾养心汤治疗心阳不振-肾阳虚衰病态窦房结综合征随机平行对照研究  

Warming Yang Xin Tang Treatment of Heart Yang of Appetite-Kidney Failure Randomized Parallel Group Study of Sick Sinus Syndrome

作　　者：王利[1] 张晓华[2] 尹小星[2] 

机构地区：[1]大连市中医医院呼吸科,大连116013 [2]大连市中医医院心病科,大连116013

出　　处：《实用中医内科杂志》2015年第1期21-23,共3页Journal of Practical Traditional Chinese Internal Medicine

摘　　要：[目的]观察温肾养心汤治疗心阳不振-肾阳虚衰病态窦房结综合征疗效。[方法]使用随机平行对照方法,将81例住院患者按病志号抽签方法简单随机分为两组。对照组41例心宝丸120mg(2丸),3次/d,口服。治疗组40例"尹小星"温肾养心汤(熟地20g,制附子10g,肉桂5g,山药、山茱萸、菟丝子、桂枝、麦冬、枸杞、当归、杜仲、人参单煎各10g),1剂/d,水煎300m L,分早晚空腹口服,150m L/次。连续治疗2周为1疗程。观测临床症状、24h动态心电图(24h QRS总数、最慢心率、平均心率、24h长R-R数)、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效21例,有效17例,无效2例,总有效率95.00%;对照组显效15例,有效15例,无效11例,总有效率73.17%;治疗组疗效优于对照组(P<0.05)。24h动态心电图两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]温肾养心汤治疗心阳不振-肾阳虚衰病态窦房结综合征,疗效满意,无明显副作用,值得推广。[Objective] To observe Warming Yang Xin Tang treatment of heart yang of appetite- Kidney failure sick sinus syndrome. [Method] Using random parallel control method,81 cases of hospitalized patients by disease Zhi No. Balloting simple random into two groups. The control group 41 cases of heart treasure pill 120mg（2pills）,3 times/d,orally. Treatment group 40 cases,＂YIN Xiaoxing＂ Warming Yang Xin Tang（Rehmannia 20 g,prepared aconite 10 g,cinnamon 5g,yam,dogwood,dodder,Gui,Radix,wolfberry,angelica,Eucommia,ginseng single fry each 10g）,1 j/d,decoction 300 m L,morning and evening hours fasting oral,150 m L/times. Two weeks of continuous treatment for a course of treatment. Observation of clinical symptoms,24 h Holter（24h QRS total,the slowest heart rate,average heart rate,24 h long RR number）,adverse reactions. A course of treatment to determine efficacy. [Results] Treatment group,21 cases markedly effective in 17 cases,2 cases,the total efficiency of 95.00%; the control group 15 cases markedly effective in 15 cases,11 cases,the total efficiency of 73.17%; treatment group than the control group（P〈0.05）. 24 h Holter improvement in both groups（P〈0.05）,improvement in the treatment group than the control group（P〈0.05）. [Conclusion] Warming Yang Xin Tang treatment of heart yang of appetite- Kidney failure sick sinus syndrome,a satisfactory effect,no side effects,it is worth promoting.

关 键 词：病态窦房结综合征 心悸 眩晕 温肾养心汤 心阳不振 肾阳虚衰 心宝丸 尹小星 老中医经验 24hQRS总数 最慢心率 平均心率 24h长R-R数 随机平行对照研究 

分 类 号：R541.74[医药卫生—心血管疾病]