HIV/HCV合并感染的相互影响及抗病毒治疗研究进展  

Research progress of interactions between HIV and HCV and antiviral therapy in co-infected patients

作　　者：冯理智 蔡卫平[1] 胡凤玉[1] 

机构地区：[1]广州医科大学附属广州市第八人民医院感染科,510060

出　　处：《传染病信息》2014年第6期333-336,384,共5页Infectious Disease Information

基　　金：国家"十二五"科技重大专项(2012ZX10001003-003);广州市科技计划项目(201300000092)

摘　　要：HIV和HCV具有相似的传播途径,主要为输血/血制品、性接触、母婴垂直及静脉注射吸毒等,因此HIV/HCV合并感染率高。HIV和HCV在体内有复杂的相互作用,使合并感染者的病程变化多样,治疗难度加大。现将HIV/HCV合并感染后病毒间相互作用机制及临床抗病毒治疗的研究进展综述如下。HIV and HCV frequently coexist because of their similar routes of transmission. Both viruses are mainly transmitted by exposure to contaminated blood or blood products, sexual contact, mother-to-child transmission and intravenous drug use. HIV/ HCV co-infection rate is high. There are complex interations of HIV with HCV and multiple disease courses in the co-infected patients. So they are more difficult to be treated. The authors describe the progress of the interactions of HIV and HCV and antiretroviral treatment in HIV/HCV co-infected patients.

关 键 词：HIV 丙型肝炎病毒 治疗学 

分 类 号：R373.51[医药卫生—病原生物学]