结核病实验室诊断新技术的临床应用  

Clinical application of the new laboratory diagnostic techniques of tuberculosis

作　　者：王心静 王仲元[2] 

机构地区：[1]解放军第三〇九医院结核病研究所临床实验室,北京100091 [2]解放军第三〇九医院全军结核病研究所,北京100091

出　　处：《传染病信息》2014年第6期373-376,共4页Infectious Disease Information

基　　金：国家自然科学基金(81071319)

摘　　要：结核分枝杆菌全基因组测序的完成,使得对结核分枝杆菌的认识进入分子水平,分子生物学和免疫学的发展为诊断新方法提供了技术平台,结核病实验室诊断技术得到快速发展。为帮助临床医生了解现有新技术,以便更好地应用,本文系统介绍现有结核病实验室诊断新技术的原理和临床应用特点。As whole-genome sequencing of Mycobacterium tuberculosis （Mtb） makes it possible to understand Mtb at the molecular level, and the development of molecular biology and immunology provides a technology platform for the new diagnostic assays, there has been a rapid development in novel diagnostic assays designed to detect Mtb and its drug resistance. To help clinicians understand the existing novel assays for better application, the authors introduce the principles and features of the existing novel diagnostic techniques of tuberculosis.

关 键 词：结核分枝杆菌 基因扩增 诊断 

分 类 号：R378.911[医药卫生—病原生物学]