磁共振3D-SPACE、3D-TrueFISP、2D-FSE-PD序列膝关节软骨成像的比较研究  

Comparative study of MR 3D-SPACE,3D-True FISP and 2D-FSE-PD sequences in articular cartilage of the knee joint

作　　者：孙岩[1] 吴雪[1] 谢萍[2] 郝跃峰[3] 胡丹[3] 刘可夫[1] 

机构地区：[1]南京医科大学附属苏州医院放射科,江苏苏州215008 [2]南京医科大学附属苏州医院超声科,江苏苏州215008 [3]南京医科大学附属苏州医院骨科,江苏苏州215008

出　　处：《实用放射学杂志》2015年第1期131-135,共5页Journal of Practical Radiology

基　　金：苏州市临床重点病种诊疗技术专项项目（LCZX201310）。

摘　　要：目的：比较三维可变反转角快速自旋回波序列（3D-SPACE）、三维真稳态进动快速成像序列（3D-Ture FISP）以及二维快速自旋回波质子像序列（2D-FSE-PD）膝关节软骨的成像质量。方法40例健康志愿者和20例患者在1.5T MR 上行3D-SPACE、3D-True FISP 和2D-FSE-PD 序列成像。比较各序列软骨信噪比（SNR）、对比信噪比（CNR）、损伤显示能力。结果3种序列中,3D-SPACE 序列的软骨信噪比、滑液与软骨的对比信噪比最高。3D-SPACE 比3D-True FISP 能更好地显示膝关节软骨的Ⅰ、Ⅱ级损伤,在软骨的Ⅲ、Ⅳ级损伤中,3D-SPACE 与3D-True FISP 无明显差异,对于各级软骨损伤,3D 序列均好于2D 序列。结论相比3D-True FISP、2D-FSE-PD 序列,3D-SPACE 序列能更好地显示膝关节软骨结构和损伤。Objective To compare the imaging quality of articular cartilage of the knee with 3D-sampling perfection with applica-tion optimized contrast using different flip angle evolutions （3D-SPACE）,3D-true fast imaging with steady-state precession （3D-True FISP）and 2D-fast-spin-echo-proto-density（2D-FSE-PD）sequences.Methods 40 healthy volunteers and 20 patients of knee joints were examined with 3D-SPACE,3D-True FISP and 2D-FSE-PD sequences at 1.5T MRI.Signal-noise ratio （SNR）,contrast-to-noise ratio （CNR）and lesion visualization of articular cartilage were compared.Results 3D-SPACE showed the highest SNR of cartilage and CNR of fluid/cartilage among the three sequences （P 〈0.05）.3D-SPACE had the better capability for showing the lev-el I 、level Ⅱcartilage injury comparing with 3D-True FISP,but no significant difference between the cartilage injury at level Ⅲ and level Ⅳ.For all levels of cartilage injury,3D sequence was better than the 2D sequence.Conclusion Compared with the 3D-True FISP sequence and 2D-FSE-PD sequence,3D-SPACE sequence can show the structure of knee and knee cartilage injury better.

关 键 词：磁共振成像 膝关节软骨 可变反转角三维快速自旋回波序列 三维真稳态进动快速成像序列 二维快速自旋回波质子像序列 

分 类 号：R445.2[医药卫生—影像医学与核医学] R322.72[医药卫生—诊断学]