良性阵发性位置性眩晕单纯复位与联合药物治疗的疗效比较  

Comparison of simple repositioning treatment and medication therapeutic alliance in management of benign paroxysm positional vertigo

作　　者：何萍[1] 徐先荣[2] 金占国[2] 刘玉华[2] 翟丽红[2] 

机构地区：[1]安徽医科大学,安徽合肥230032 [2]空军总医院全军临床航空医学中心,航空航天眩晕诊疗研究中心,北京100142

出　　处：《解放军医学院学报》2015年第1期27-29,共3页Academic Journal of Chinese PLA Medical School

基　　金：国家科技部"十二五"科技支撑计划项目(2012BAI12B02)~~

摘　　要：目的比较单纯复位治疗与联合药物治疗嵴顶型水平半规管良性阵发性位置性眩晕(hoeizontal semicircular canal benign paroxysm positional vertigo,HSC-BPPV)的疗效及复发情况。方法收集空军总医院眩晕中心2013年10月-2014年6月经Roll-maneuver试验诊断为嵴顶型HSC-BPPV患者62例,随机分为复位治疗组(A组)32例予以单纯复位,复位联合药物治疗组(B组)30例在复位治疗的基础上加用前列地尔、桂哌齐特静脉注射,倍他司汀片口服。于首次治疗7 d、28 d后进行疗效评定,随访3个月观察复发情况。结果治疗7 d后B组痊愈56.7%,有效40.0%,无效3.3%;A组痊愈46.9%,有效50.0%,无效3.1%。B组痊愈率高于A组,但差异无统计学意义(P>0.05),总有效率无统计学差异(P>0.05)。治疗28 d后B组痊愈率96.67%,有效率3.33%,无效0,总有效率100%;A组痊愈率78.12%,有效率21.88%,无效0,总有效率100%。B组痊愈率高于A组(P<0.05)。随访3个月,B组3例(10.0%)复发,A组10例(31.25%)复发,两组差异有统计学意义(P<0.05)。结论复位法治疗嵴顶型HSC-BPPV有效率高、安全性好,是治疗的首选方法,复位联合药物治疗可提高其治愈率、缩短治愈时间、减少复发率。Objective To compare the efficacy and recurrence of simple repositioning treatment and medication therapeutic alliance in treatment of horizontal semicircular canal ridge crest benign paroxysm positional vertigo. Methods Sixty-two patients with horizontal semicircular canal ridge crest benign paroxysm positional vertigo who were diagnosed in Vertigo Clinical Service Air Force General Hospital of PLA by Roll-maneuver test were included in this study. Thirty-two cases in repositioning group（group A） were treated with simple repositioning and the other thirty cases in medication alliance treated group（group B） received simple repositioning treatment plus Alprostadil, Cinepazide and Betahistine Tablets. The curative effects of both groups were analyzed at 7 d and 28 d after treatment, and recurrence was observed after three months. Results After 7 d treatment, the recovery rate of group B was 56.7% with the efficiency of 40.0% and useless rate of 3.3%. The recovery rate of group A was 46.9% with the effective power of 50.0% and useless rate of 3.1%. The recovery rate was higher in group B than group A with no statistical difference（P 0.05）,and also no statistic difference was found in total effective rate（P 0.05）. After 28 d treatment, the recovery rate of group B was 96.67% with the efficiency of 3.33% and useless rate of 0, and the recovery rate of group A was 78.12% with the efficiency of 21.88% and useless rate of 0. The recovery rate was higher in B group and it showed significant difference（P 0.05）. In the following three months, the recurrence of group B was 10.0%（n=3） and 31.25% in group A（n=10） which showed statistical difference（P 0.05）. Conclusion The repositioning treatment is a preferred method to cure horizontal semicircular canal ridge crest benign paroxysm positional vertigo, medication therapeutic alliance can elevate the recovery rate, shorten cure time and decrease recurrence rate.

关 键 词：良性阵发性位置性眩晕 复位治疗 药物治疗 

分 类 号：R85[医药卫生—航空、航天与航海医学]