洛阳正骨传统方药解毒饮对严重创伤后SIRS患者凝血功能的临床观察  

Traditional Prescription of Luoyang Orthopedic Jieduyin on Blood Coagulation in trauma patients with SIRS

作　　者：冯鹏[1] 马虎升[1,2] 樊金辉[1] 

机构地区：[1]福建中医药大学,福建福州350108 [2]河南省洛阳正骨医院,河南省骨科医院,河南洛阳471002

出　　处：《中医药临床杂志》2015年第1期94-96,共3页Clinical Journal of Traditional Chinese Medicine

基　　金：河南省中医药科学研究专项课题(2014ZY02095)

摘　　要：目的:研究并探讨洛阳正骨传统药物解毒饮对严重创伤后全身炎症反应综合征患者凝血功能的影响。方法:将60例严重创伤后全身炎症反应综合征患者随机分为2组。对照组30例给予常规综合治疗;治疗组30例在此基础上早期应用解毒饮。监测治疗前、治疗后3d、5d、7d凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、血浆纤维蛋白原(FIB)、血浆D-二聚体(D-D)及血小板(PLT)动态演变情况,并进行急性生理学和慢性健康状况Ⅱ(APACHEⅡ)评分。结果:治疗组于治疗3、5d后上述实验室检测指标均有改善,且与对照组比较有显著性差异,治疗第7d 2组凝血功能上无明显差别;治疗前后。2组APACHEⅡ评分均较治疗前下降且治疗7d后治疗组较对照组下降明显。结论:解毒饮可以减轻创伤后SIRS患者的炎症反应,改善其凝血功能,在一定程度上改善SIRS患者病情。Objective：To observe the clinical efficiency on treating on trauma patients with SIRS with Jieduyin decoction and discuss the innuence of Jieduyin decoction for regulating blood Coagulation Methods： A randomized,double—blind clinical trial was performed with 60 patients who had undergone orthopedic surgery in our hospita1.They were equally assigned to tow groups,in treatment group 30 cases were given administmtion with Jieduyin,in control group 30 cases were given administration with routine treatment,after 7 days. To compare APTT、TT、FIB、D-D、PLT and the scores of acute physiology and chronic health evaluation Ⅱ（APACHE Ⅱ） were observed in the two groups.Results：after 3days、5days of treatment,the coagulation function ie better than control group,after 7days of treatment,there is on difference; APACHE Ⅱ scores in the treatment group were lower than those in the control group. Conclusion：Jieduyin can reduce post-traumatic inflammatory reaction of SIRS patients,improve the function of blood coagulation,Improve the SIRS patients.

关 键 词：创伤 全身炎症反应综合征 解毒饮 凝血功能 

分 类 号：R674.9[医药卫生—外科学]