苯丙氨酸衍生类多肽聚合物纳米棒的制备及表征  

Preparation and characterization of phenylalanine-derived peptide-like polymer nanorods

作　　者：马杰[1] 杨建涛[1] 曾小玲[1] 翁文[1] 

机构地区：[1]闽南师范大学化学与环境学院,福建漳州363000

出　　处：《应用化工》2015年第2期261-263,共3页Applied Chemical Industry

基　　金：福建省自然科学基金杰出青年基金项目(2012J06005);国家级大学生创新创业训练计划项目(201310402020);闽南师范大学研究生科研立项(1300-1314)

摘　　要：以手性化合物苯丙氨酸作为前驱体,于油酸中通过高温溶剂法一步合成了具有强疏水性的白色类多肽聚合物,扫描电子显微镜分析表明,产物自组装成纳米棒结构。利用核磁共振、紫外光谱、红外光谱、荧光光谱、基质辅助激光解析电离飞行时间质谱等对产物进行了分析。圆二色光谱分析表明,产物仍具有手性性质。该合成方法简单方便,提供了一种合成类多肽聚合物的途径。White hydrophobic peptide-like polymer was prepared from phenylalanine by one-step solvothermal method with oleic acid as reaction media. SEM images showed that the product can simultaneously self-assemble to form nanorod structure under this condition. The as-prepared product was further characterized by NMR,UV-Vis spectroscopy,IR spectroscopy,fluorescence spectroscopy,and matrix assisted laser desorption ionization/time of flight（MALDI-TOF） mass spectroscopy. The circular dichroism spectra showed that the obtained polymer still possessed chirality property. The facile method provides an approach to synthesize peptide-like polymer.

关 键 词：苯丙氨酸 类多肽聚合物 纳米棒 手性 

分 类 号：TQ421.12[化学工程]