磁共振成像技术在肝细胞癌中的应用进展  

Progresses in magnetic resonance imaging of hepatocellular carcinoma

作　　者：蒋涵羽 刘曦娇[2] 宋彬[2] 

机构地区：[1]四川大学华西临床医学院,2010级8年制研究生成都610041 [2]四川大学华西医院放射科,成都610041

出　　处：《磁共振成像》2015年第2期91-97,共7页Chinese Journal of Magnetic Resonance Imaging

基　　金：国家自然科学基金面上项目(编号:81171338;81471658)

摘　　要：目的探讨磁共振成像在肝细胞癌诊断、预后评价、治疗方案选择、疗效评估中的应用进展。材料与方法收集并分析国内外最新相关文献。结果功能磁共振成像及肝脏特异性对比剂等磁共振新技术的发展与应用使磁共振成像不仅有助于早期诊断肝细胞癌,还可以反映肿瘤的发病机制、生物学行为特点和细胞水平的基因表达异常,为肝细胞癌的预后评价、治疗方案的选择及疗效评估提供了重要信息。结论磁共振成像是诊断、评估、监测、随访肝细胞癌重要的有效手段。Objective： To review the recent advances of magnetic resonance imaging （MRI） techniques in the diagnosis, prognosis,treatment decision making and early assessment of therapeutic response of hepatocellular carcinomas （HCC）. Materials and Methods： The newest related published literatures about the MR imaging of HCC were collected and analyzed. Results： With recent development and application of the functional MRI and liver-specific MR contrast agents in HCC, MRI is not only able to diagnose HCC in the early stage, but also reveal the tumor pathogenesis, biological behaviors and abnormal gene expressions at cellular level, thus providing significant information for the prognosis evaluation, treatment decision making and response assessment of HCCs. Conclusions： MR imaging plays a vital and effective role in the diagnosis, evaluation, surveillance and follow-up of HCC.

关 键 词：肝细胞癌 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R735.7[医药卫生—诊断学]