伤椎内植骨联合骨水泥强化治疗重度骨质疏松椎体压缩骨折初步疗效观察  

Primary curative effect of vertebral body bone graft and bone cement augmentation in treatment of severe osteoporotic vertebral body compression fractures

作　　者：王云清[1] 王建强[1] 李华[1] 王斌[1] 朱自强[1] 

机构地区：[1]徐州医学院第二附属医院骨科,江苏徐州221006

出　　处：《中国骨与关节损伤杂志》2015年第1期54-56,共3页Chinese Journal of Bone and Joint Injury

基　　金：徐州市科学技术局自然科学基金(XZZD1356)

摘　　要：目的探讨椎内植骨联合骨水泥强化治疗重度骨质疏松椎体压缩骨折（SVCF）的初步疗效。方法对非植骨组（30例）和植骨组（19例）患者手术前后疼痛程度、病变椎体前缘高度、Cobb角,以及骨水泥渗漏、邻近椎体骨折等并发症情况进行观察,并进行统计分析。结果无肺栓塞及神经并发症发生,2组患者疼痛均明显缓解,伤椎高度和Cobb角矫正较术前明显改善,差异有统计学意义（P〈0.05）。随访2-5年,平均3年2个月,骨水泥渗漏非植骨组5例,植骨组1例,邻近椎体再骨折非植骨组4例,植骨组1例。2组在骨水泥渗漏率、邻近椎体骨折发生率方面比较,差异有统计学意义（P〈0.05）。结论椎内植骨联合骨水泥强化在降低骨水泥渗漏、邻近椎体骨折发生率上具有优势,是一种较理想的治疗方法。Objective To explore the primary curative effect of vertebral body bone graft and bone cement augmentation in the treatment of severe osteoporotic vertebral body compression fractures. Methods The curative effect was observed and the statistical difference between the control group（30 cases） and the bone graft group（19 cases） before and after operation were analyzed. The therapeutic efficacy was assessed by visual analogue scale（VAS）, the anterior vertebral height, Cobb angle, bone cement leakage and adjacent vertebral fracture. Results No neurological symptomatic and other severe complications were found in all patients. The VAS scores, the anterior vertebral height and Cobb angle improved significantly after the surgery（ P 〈0.05）. All patients were followed up for 2-5 years, average 3 years and 2 months, the bone cement leakage occurred in 5 cases of the control group and 1 case in the bone graft group, the adjacent vertebral fracture occurred in 4 cases of the control group and 1 case in the bone graft group. There was significant difference between two groups in the bone cement leakage and adjacent vertebral fracture（P 〈0.05）. Conclusion The treatment for severe osteoporotic vertebral body compression fractures by vertebral body bone graft and bone cement augmentation can obtain satisfactory curative effect. It is an ideal treatment method.

关 键 词：椎内植骨 骨水泥强化 重度骨质疏松 椎体压缩骨折 

分 类 号：R687.3[医药卫生—骨科学]