骨科内固定材料镁合金的生物学研究进展  

The biological progress of magnesium alloys application as orthopaedics internal fixation material

作　　者：王富勇[1] 陶海荣[1] 

机构地区：[1]上海交通大学医学院附属第三人民医院,上海201900

出　　处：《中国矫形外科杂志》2015年第4期322-324,共3页Orthopedic Journal of China

基　　金：上海交通大学医学院课题资助(编号:11xj21052)

摘　　要：[目的]综述骨科内固定材料镁合金的生物学研究进展。[方法]查阅近年有关可降解镁合金研究的相关文献,并进行总结。[结果]本文就含不同合金元素的镁合金、含表面活性成分的镁合金、多孔镁合金3个方面来叙述镁合金的生物学性能,但镁合金在体内降解机制、对生物体的作用尤其是远期影响还缺乏系统研究,镁合金的体内降解速度亦未得到有效控制。[结论]镁合金具有成为骨科内固定材料的潜力,但最终在应用于临床前仍需进行深入、系统的研究。[Objective]To review the biological progress of magnesium alloys application as orthopaedics internal fixation material. [Method]Recent literature was extensively reviewed and summarized,concerning the magnesium alloys as orthopaedics internal fixation material. [Result]In this paper,magnesium alloys containing different alloy elements,magnesium alloys containing surface active ingredients,and porous magnesium alloy are used to describe biological performance of magnesium alloys. However,the degradation mechanism of magnesium- based materials in the physiological environment and long- term effect on body are not available. The modulation of the corrosion rate of magnesium alloys must also be accomplished. [Conclusion]Magnesium alloys have the potential to serve as degradable implants for orthopaedic applications,but a great deal of further investigation is still necessary.

关 键 词：骨科 内固定材料 镁合金 

分 类 号：R687[医药卫生—骨科学]