2008-2013年鲍曼不动杆菌的分布及耐药分析  

Analyze the distribution and drug resistance of Acinetobacter baumannii from 2008 to 2013

作　　者：伍世钢 罗强[2] 

机构地区：[1]广州市荔湾区人民医院检验科,广东广州510370 [2]广东省中医院检验科,广东广州510370

出　　处：《热带医学杂志》2015年第1期84-87,共4页Journal of Tropical Medicine

摘　　要：目的监测临床标本中鲍曼不动杆菌的分离率、分布特点及耐药情况,为临床抗菌药物的使用提供依据。方法对2008-2013年临床分离的1 210株鲍曼不动杆菌分布科室、感染特点及15种常用抗生素耐药率进行统计分析。结果分离的鲍曼不动杆菌以呼吸道感染为主,重症监护病房(ICU)为主要检出科室,标本来源以痰最多占84.6%,其次为分泌物。鲍曼不动杆菌检出率呈逐年增高趋势,从2008年的7.1%上升至2013年的11.9%,并有季节性差异,以二、三季度分离菌株数较多。鲍曼不动杆菌对15种常用抗生素耐药率呈不同程度的增加,全耐药菌株明显增多,从2008年的0株上升至2013年的50株。结论鲍曼不动杆菌的分离率逐年增加,以二、三季度感染率较高,泛耐药性愈加严重,全耐药菌株明显增加。合理使用抗生素、控制医院感染的发生乃当务之急。Objective To understand the isolation rate, distribution and drug resistance of Acinetobacter baumannii in recent6 years,and provide basis for clinical use of antibiotics. Methods Data of 1210 strains Acinetobacter baumannii from clinical specimen was analyzed, and it′s the distribution characteristic and resistance to 20 kinds of antibiotics were determined for 6years. Results According to data of the 6 years infection surveillance, Acinetobacter baumannii was isolated mostly from sputum in our hospital, accounted for 84.6%, followed by secretion. The ward with the highest incidence was ICU.Acinetobacter baumannii isolation rate increased year by year, 11.9% in 2013 to 7.1% in 2008. Infection rates showed seasonal differences, mainly in the second and third quarter of each year. Antibiotic resistance rates of 15 antibiotics were increased in different degree. Pan Drug Resistant Acinetobacter baumannii was significantly increased, from 0 in 2008 to 50 strains in 2013. Conclusion The isolation rate of Acinetobacter baumannii was increasing year by year; infection mainly happened in the second and third quarter. Pan drug resistance was more and more serious. Attention should be paid for using antibiotics rationally and controlling the incidence of nosocomial infection is the top priority of the moment.

关 键 词：鲍曼不动杆菌 分离率 耐药率 全耐药菌株 

分 类 号：R378.99[医药卫生—病原生物学]