反复输血的不完全抗体阳性的研究  

Study on the Positive Rate of Incomplete Antibody in Patients after Repeated Blood Transfusion

作　　者：符芳玲[1] 伍燕[1] 李应明[1] 

机构地区：[1]海口市人民医院输血科,海口570208

出　　处：《医学综述》2015年第3期564-565,共2页Medical Recapitulate

摘　　要：目的探讨反复输血后不完全抗体的阳性率及其临床意义。方法选取2010年12月至2012年7月来海口市人民医院的1498例反复申请输血者作为研究对象,另选择同期1500例首次输血者作为首次输血组。采用Dia Mcd微柱凝胶免疫技术(Ig G卡)对申请输血者的血液标本进行不规则抗体筛查,同时对不规则抗体阳性的标本进行抗体鉴定。结果反复输血者的不完全抗体阳性率为3.07%(46/1498),而首次输血者的不完全抗体阳性率为0.27%(4/1500),两者比较差异有统计学意义(P<0.05)。46例反复输血者以抗-E抗体阳性最多,为22例,占47.8%。结论重视受血者不完全抗体的检测对预防和减少输血不良反应、保证输血安全有重要意义。Objective To explore the positive rate of incomplete antibody in patients after repeated blood transfusion and its clinical significance. Methods A total of 1498 patients who had received repeated blood transfusion in Haikou People＇S Hospital from Dec. 2010 to Jul. 2012 were selected as the research objects,and 1500 patients who had received blood transfusion for the first time during the same period in the hospital were selected as the control group. The blood preparations of all the patients were detected by immune Dia Mcd micro-column gel technology（ Ig G） for irregular antibody screening,and positive preparations of irregular antibody were conducted antibody identificaiton at the same time. Results The positive rate of incomplete antibody in patients received repeated blood transfusion was 3. 07%（ 46 /1498）,and that of patients received the first blood transfusion was 0. 27%（ 4 /1500）,there was statistically significant difference between the two groups（ P〈0. 05）. There were 22 cases of patients with anti-E antibody positive out of the 46 positive cases received repeated blood transfusion,accounting for 47. 8%（ 22 /46）. Conclusion Clinicians should attach great importance to the detection of incomplete antibody in blood recipients,so as to prevent and reduce the adverse reactions,and ensure the safety of blood transfusion.

关 键 词：受血者 不完全抗体 抗-E抗体 

分 类 号：R446.11[医药卫生—诊断学]