天津市含麻疹成分疫苗首剂接种率评价  

Evaluation on Immunization Coverage Rate of the First-Dose Measles Containing Vaccine in Tianjin

作　　者：丁亚兴[1] 孙静[1] 田宏[1] 陈伟[1] 黄海涛[1] 万丽霞[1] 高志刚[1] 张颖[1] 

机构地区：[1]天津市疾病预防控制中心免疫规划科,天津300011

出　　处：《预防医学情报杂志》2015年第2期111-113,共3页Journal of Preventive Medicine Information

摘　　要：目的对天津市含麻疹成分疫苗（Measles Containing Vaccine,MCV）首剂（MCV1）接种率进行评价。方法2009-2012年采用多阶段随机抽样法抽取天津市8月龄～6岁健康儿童开展麻疹血清学抗体监测,以麻疹抗体阳性率来评价该年龄组MCV1接种率。结果 2009-2012年天津市8月龄～6岁组MCV1调查接种率（Investigated Immunization Coverage Rate,IIR）分别为92.59%、98.25%、99.04%和98.53%;当疫苗效力（Vaccine Efficacy,VE）取82.9%和95%时,2009-2011年估算接种率（Estimated Immunization Coverage Rate,EIR）分别为15.45%、60.67%、77.82%和38.46%、84.07%、92.31%;免疫规划信息系统统计的全市MCV1接种率分别为：95.46%、96.47%、98.11%和99.03%。血清学监测抗体阳性率2009-2012年分别为94.22%、97.07%、96.91%和95.45%,经统计分析,除2012年外,IIR、EIR和信息系统接种率估算出来的抗体阳性率和血清学监测阳性率之间有显著性差异（P〈0.05）。结论血清学监测能评价疫苗接种率,真实反映人群免疫力。Objective To evaluate the immunization coverage rate of the first dose of measles containing vaccine （ MCV1 ） in Tianjin. Methods Multistage random sampling method was applied to draw subjects aged from 8 months to 6 years for measles serological surveillance, and positive rate of measles antibody was adopted to e- valuate the immunization coverage rate of MCV1. Results The MCV1 investigated immunization coverage rate of the participant in 2009 -2012 were respectively 92.59% , 98.25% , 99.04% and 98.53%. When vaccine efficacy set as 82. 9% and 95% , the estimated immunization coverage rate of MCV1 in 2009 - 2011 was re- spectively 15.45%, 60. 67%and 77.82%, and 38.46% , 84. 07%, and 92. 31%. Immunization informa- tion system coverage rate of MCV1 in 2009 -2012 were respectively 95.46%, 96.47%, 98.11% and 99.03%. The measles antibody positive rate of serological surveillance in 2009 -2012 was 94.22%,97.07%, 96.91% and 95.45%. Antibody positive rate of serological surveillance and estimated positive rate by ways of IIR, EIR and information system was statistical different, except 2012. Conclusion Serological surveil- lance can evaluate vaccine immunization coverage rate and exactly reflect population immunity.

关 键 词：含麻疹成分疫苗 调查接种率 估算接种率 抗体阳性率 

分 类 号：R186[医药卫生—流行病学]