脊髓灰质炎活疫苗相关麻痹型脊灰病例报告  

A Case Report of Oral Poliomyelitis Live Vaccine Caused Paralytic Polio

作　　者：柳国锋 

机构地区：[1]承德市卫生监督局,河北承德067000

出　　处：《预防医学情报杂志》2015年第2期147-148,共2页Journal of Preventive Medicine Information

摘　　要：目的报告1例口服脊髓灰质炎(脊灰)减毒活疫苗引起的疫苗相关麻痹型脊灰病例,为预防接种工作提供参考。方法由河北省疾病预防控制中心(CDC)在该省急性迟缓性麻痹(AFP)病例监测系统报告病例中进行病毒分离,发现脊灰病毒阳性标本送国家CDC鉴定,综合病例的流行病学、临床表现和实验结果,由省级专家组做出诊断鉴定。结果患儿为首次服苗,23d后出现麻痹,60d后双下肢残留麻痹,国家级实验室鉴定结果为Ⅱ型脊灰疫苗相关株。结论该病例诊断鉴定为口服脊髓灰质炎减毒活疫苗引起的疫苗相关麻痹型脊灰病例。Objective To report an oral poliomyelitis live vaccine caused paralytic polio and to provide references for prevention and control measures. Methods The virus isolation of the case reported from Acute Flaccid Pa- ralysis Surveillance System was conducted by Hebei CDC. Diagnosis and authentication was carried out with synthetical analysis of epidemic features, clinical manifestation and lad results by provincial experts. Results This child case was the first time to take the vaccine and exhibited paralysis 23 days later. Sixty days later, both lower extremities were left with residual paralysis. The national lab confirmed the pathogenesis was type - Ⅱ oral poliovirus vaccine bacterial strain. Conclusion This is a paralytic polio case caused by poliomye- litis live vaccine.

关 键 词：预防接种 脊髓灰质炎减毒活疫苗 疫苗相关病例 

分 类 号：R186[医药卫生—流行病学]