甲状腺功能亢进与moyamoya综合征的研究进展  

Research Progess in Hyperthyroidism and Moyamoya Syndrome

作　　者：肖伏龙[1] 高培毅[1,2] 

机构地区：[1]首都医科大学附属北京天坛医院放射科,北京100050 [2]北京市神经外科研究所

出　　处：《中国卒中杂志》2015年第2期170-174,共5页Chinese Journal of Stroke

基　　金：北京市自然科学基金资助项目(7122029)

摘　　要：与moyamoya病相比,moyamoya综合征尚未形成典型的异常血管网,moyamoya综合征中颅内动脉狭窄可能是moyamoya病的一个亚型或早期表现,且与moyamoya病存在相同的病理生理学机制。甲状腺功能亢进相关的moyamoya综合征的病理生理学机制包括自身免疫性破坏、血流动力学异常、动脉粥样硬化及交感神经兴奋性增加等,诊断和治疗上,应密切关注甲状腺素水平的变化。本文对甲状腺功能亢进相关的moyamoya综合征的病理生理学机制及临床诊断治疗中应注意的问题做一综述。The abnormal vascular network found in moyamoya syndrome is different from that in moyamoya disease.Stenosis in intracranial vessels found in moyamoya syndrome may be a subtype or an early stage of moyamoya disease.The pathophysiology in moyamoya syndrome may have some common ground with moyamoya disease.The pathophysiology in moyamoya syndrome associated with hyperthyroidism includes autoimmune disorder,abnormal hemodynamic,arteriosclerosis and increased sympathetic activation.Changes in thyroxin level should be concerned in clinical practice.In this review,we summarize the pathophysiology of moyamoya syndrome associated with hyperthyroidism and some points in clinical diagnosis and treatment.

关 键 词：甲状腺功能亢进 moyamoya综合征 MOYAMOYA病 

分 类 号：R581.1[医药卫生—内分泌]