Aminobromination of Ethyl α-Cyanocinnamate Derivatives with 1,3-Dibromo-5,5-dimethylhydantoin（DBDMH） as Nitrogen and Halogen Sources  

作　　者：CHEN Zhanguo LIU Yali HU Junli LIU De'e 

机构地区：[1]Key Laboratory for Macromolecular Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710119, P R. China

出　　处：《Chemical Research in Chinese Universities》2015年第1期65-70,共6页高等学校化学研究（英文版）

基　　金：Supported by the Natural Science Foundation of Shaanxi Province, China（No.2009JM2001）, the Innovation FoundatiOn of Pastgraduate Cultivation of Shaanxi Normal University, China（No.2008CXB009） and the Fundamental Research Funds for the Central Universities of China（No.GK261001095）.

摘　　要：1,3-Dibromo-5,5-dimethylhydantoin（DBDMH） was found to be a new and efficient nitrogen/halogen source for the aminobromination of ethyl a-cyanocinnamate derivatives catalyzed by K3PO4. The reaction afforded the aminobrominated products in high yields at room temperature, and the full regiospecificity of all the products were achieved. A possible pathway involving a Michael addition for this aminobromination was suggested.1,3-Dibromo-5,5-dimethylhydantoin（DBDMH） was found to be a new and efficient nitrogen/halogen source for the aminobromination of ethyl a-cyanocinnamate derivatives catalyzed by K3PO4. The reaction afforded the aminobrominated products in high yields at room temperature, and the full regiospecificity of all the products were achieved. A possible pathway involving a Michael addition for this aminobromination was suggested.

关 键 词：AMINOBROMINATION Ethyl a-cyanocinnamate derivative 1 3-Dibromo-5 5-dimethylhydantoin（DBDMH） 

分 类 号：O626.23[理学—有机化学] S948[理学—化学]