降钙素原等炎症标志物检测在儿童手足口病中的意义  

Significance of procaicitonin and other inflammatory markers in pediatric patients with HFMD

作　　者：段发强[1] 邓明惠 蔺咏梅[2] 侯轩[1] 辜依海[1] 

机构地区：[1]西安交通大学附属三二〇一医院微免科,陕西汉中723000 [2]西安交通大学附属三二〇一医院感染病性疾病科,陕西汉中723000

出　　处：《国际检验医学杂志》2015年第4期446-448,共3页International Journal of Laboratory Medicine

摘　　要：目的探讨降钙素原(PCT)、C反应蛋白(CRP)、白细胞(WBC)等炎症标志物检测在手足口病患儿临床诊断中的意义。方法分析138例手足口患儿(观察组)和50例健康儿童(对照组)的PCT、WBC计数、中性粒细胞计数(NC)、淋巴细胞(Ly)、CRP、免疫球蛋白等常见实验室指标,并进行比较。结果观察组患儿PCT、CRP、WBC、NC、Ly%、IgM等水平均高于对照组,差异有统计学意义(P<0.05);IgG、IgA水平均低于对照组,差异有统计学意义(P<0.05)。结论 PCT、WBC、NC、Ly、CRP等炎症标志物和免疫球蛋白的检测可为小儿手足口病的诊断提供依据。Objective To investigate the significance of procalcitonin（PCT）,C-reactive protein（CRP）,white blood cell（WBC）and other inflammatory markers in the diagnosis of pediatric patients with HFMD.Methods 138 cases of pediatric patients with foot and mouth disease（study group）and 50 cases of healthy children（control group）were recruited in the study.Procalcitonin（PCT）,white blood cell（WBC）,neutrophil count（NC）,lymphocyte count（Ly）,immunoglobulins,C-reactive protein and other indicators were determined and compared.Results PCT,CRP,WBC,NC,Ly%and IgM levels were higher in study group than those in control group,the differences were all statistically significant（P〈0.05）;IgG,IgA levels in control group were lower than that in control group,the differences were statistically significant（P〈0.05）.Conclusion PCT,WBC,NC,Ly,CRP and IgA,IgG,IgM can provide experimental evidence for diagnosis of children with hand foot and mouth disease.

关 键 词：降钙素原 白细胞 C反应蛋白 免疫球蛋白 手足口病 炎性标志物 

分 类 号：R725.1[医药卫生—儿科] R446.1[医药卫生—临床医学]