肾移植受者服药依从性与健康相关生活质量的相关研究  

Correlation between Medication Compliance and Health-related Quality of Life of Kidney Transplant Recipient

作　　者：刘红霞[1] 滕沙 张淑萍[1] 张文馨[1] 

机构地区：[1]北京中医药大学护理学院,北京100102

出　　处：《护理学报》2015年第3期33-37,共5页Journal of Nursing（China）

基　　金：国家自然科学基金面上项目(81171860)

摘　　要：目的了解肾移植受者服药依从性现状及其与健康相关生活质量的相关关系。方法对纳入研究的196例患者,运用简明健康调查表SF-36(the Medical Outcomes Study 36-item Short-form Health Survey,MOS SF-36)及肾移植受者服药依从性问卷进行调查。采用Pearson相关及多元线性回归来分析服药依从性与健康相关生活质量的关系。结果肾移植受者的服药依从性与健康相关生活质量的精神健康领域及生理领域均存在正相关,分别为精神健康领域(r=0.603,P<0.01)、生理领域(r=0.214,P<0.01)。进入精神健康领域回归方程的有按时服药、漏服药、按剂量服药条目,综合解释了精神健康领域变异的48.7%。进入生理领域回归方程的为漏服药条目,但仅解释了生理领域4.6%的变异。结论肾移植术后患者的服药依从性与健康相关生活质量之间存在一定的正相关,与生活质量的精神健康领域正相关程度密切;采取相应的干预措施提高肾移植受者的服药依从性,有助于提高肾移植受者的健康相关生活质量。Objective To understand the status quo of medication compliance and its correlation with health-related quality of life（HRQL） of kidney transplant recipient（KTC）. Methods The Medical Outcomes Study 36-item Short-form Health Survey（MOS SF-36） and medication compliance questionnaire of KTC were used to investigate 196 patients. Pearson correlation analysis and multiple linear regression were used to analyze the relationship between HRQL and medication compliance. Results Medication compliance of KTC was related with psychological health（r=0.603, P〈0.01） and physical domain（r=0.214, P〈0.01）. Items entered into the regression equation of psychological health included timely medication-taking, missing the dose and taking the correct dose and which explained 48.7% of the variances in psychological health and the item of missing the dose entered into the regression equation of physical domain but only explained 4.6% of the variance. Conclusion Medication compliance is related with and HRQL,particularly with psychological health. Corresponding intervention benefits the improvement of medication compliance and eventually the improvement of patients＇ HRQL.

关 键 词：肾移植受者 服药依从性 健康相关生活质量 

分 类 号：R473.6[医药卫生—护理学]