冠心病患者冠状动脉病变程度与左心室舒张末压的相关性  

Relationship between severity of coronary lesion and left ventricular end-diastolic pressure in patients with coronary heart disease

作　　者：庞兴学[1] 杨清[2] 罗智[1] 纪冬梅[1] 王媛[1] 白莹[1] 樊燕琴[1] 陈晓丽[1] 刘宏[1] 

机构地区：[1]北京老年医院心内科,北京100095 [2]首都医科大学附属北京安贞医院

出　　处：《中国循证心血管医学杂志》2015年第1期84-86,共3页Chinese Journal of Evidence-Based Cardiovascular Medicine

摘　　要：目的探讨冠心病患者冠状动脉病变严重程度与左心室舒张功能的关系。方法选择2009年间至2011年12月在北京老年医院心内科住院并行冠状动脉造影的患者359例,根据冠状动脉造影结果,将入选患者分为冠心病组(n=135)和非冠心病组(n=224),所有入选患者在冠状动脉造影时同步用导管法测定左心室舒张末压;根据冠状动脉造影进行冠脉病变SYNTAX积分,并研究SYNTAX积分与左心室舒张末压的相关性。结果左心室舒张末压在冠心病组与非冠心病组差异具有统计学意义[(21.72±3.21)mm Hg vs.(3.71±0.46)mm Hg,P<0.01],左心室舒张末压与SYNTAX积分呈显著正相关关系(r=0.89,P<0.01)。结论冠心病患者左心室舒张功能与冠状动脉病变严重程度呈正相关。Objective To investigate the relationship between severity of coronary lesion and left ventricular end-diastolic pressure （LVEDP） in patients with coronary heart disease （CHD）. Methods CHD patients （n=359） with coronary angiography （CAG） were divided into CHD group （n=135） and non-CHD group （n=224）. All patients were given CAG and LVEDP detection at the same time. SYNTAX integrals of coronary lesion were calctdated according to CAG outcomes, and correlation between SYNTAX integral and LVEDP was studied. Results The difference in LVEDP had statistical significance between 2 groups [（21.72 ± 3.21） mmHg vs.（3.71 ± 0.46） mmHg, P〈0.01], and LVEDP was greatly correlated to SYNTAX integral （r=0.89, P〈0.01）. Conclusion The left ventricular diastolic function is positively correlated to severity of coronary lesion in CHD patients.

关 键 词：冠状动脉粥样硬化性心脏病 左室舒张末压 相关性 

分 类 号：R541.4[医药卫生—心血管疾病]