颅内真菌性肉芽肿的诊断及外科治疗  

Diagnosis and surgical treatment of intracranial fungal granuloma

作　　者：张治元[1] 王汉东[1] 樊友武[1] 李杰[1] 王笑亮[1] 王海[1] 

机构地区：[1]南京军区南京总医院神经外科,210002

出　　处：《中国微侵袭神经外科杂志》2015年第2期71-73,共3页Chinese Journal of Minimally Invasive Neurosurgery

摘　　要：目的探讨颅内真菌性肉芽肿(IFG)的诊断和外科治疗。方法回顾性分析经手术治疗的9例IFG病人的临床病史、体征、影像学特点、外科治疗及预后。结果病灶全切除7例,次全切除1例,部分切除1例。病理检查确诊为IFG。8例经手术及抗真菌药物治疗后痊愈,1例术后脑水肿加重,放弃治疗后死亡。结论手术标本病理检查是IFG的可靠确诊方法。手术切除结合抗真菌药物治疗是IFG的主要治疗方法。经手术治疗结合抗真菌药物治疗,多数IFG病人预后良好。Objective To explore the diagnosis and surgical treatment of intracranial fungal granuloma（IFG）. Methods The clinical data of 9 patients with IFG, including the clinical history, signs, imaging features, surgical treatment and prognosis, were analyzed retrospectively. Results Total resection was achieved in 7 patients, subtotal resection in 1 and partial resection in 1. The diagnosis of IFG was confirmed by pathological examination. Eight IFG patients were cured by surgery and antifungal therapy, 1 IFG patient with serious postoperative cerebral edema, gave up further treatment and died at last. Conclusions Pathological examination of surgical specimens is the most reliable method for the diagnosis of IFG. Surgical resection combined with antifungal therapy is the main treatment for IFG. Most of IFG patients can have good prognosis after surgical resection combined with antifungal therapy.

关 键 词：肉芽肿 真菌 诊断 神经外科手术 

分 类 号：R651.11[医药卫生—外科学] R519[医药卫生—临床医学]