磁共振扩散张量成像在婴幼儿脑瘫诊断中的应用价值  

Significance of Applying DTI in the Diagnosis of Cerebral Palsy in Infants with Developmental Delays

作　　者：张朋[1] 刘鹏[1] 刘杰[1] 王颖[1] 高修成[1] 张见[1] 

机构地区：[1]南京医科大学附属南京儿童医院放射科,江苏南京210008

出　　处：《中国医疗设备》2015年第2期53-55,共3页China Medical Devices

摘　　要：目的探讨磁共振张量成像(DTI)在婴幼儿脑瘫诊断中的应用价值。方法选取33例脑瘫婴幼儿作为脑瘫组,33例正常婴幼儿作为对照组,分别对其行DTI检查。观察神经纤维束的改变,研究DTI成像特点及其与脑瘫的相关性,并采用统计学方法比较脑瘫组和对照组感兴趣区的各向异性(FA)值。结果 33例脑瘫患儿中,23例伴有不同部位和不同程度的神经纤维束稀疏、中断及走行异常,10例患儿神经纤维束改变不明显;脑瘫组患儿感兴趣区的FA值较低,与对照组相比有显著差异(P<0.05)。结论 DTI异常表现与脑性瘫痪具有相关性,DTI检查有助于对婴幼儿脑瘫做出早期诊断,为制定合理的诊疗方案提供依据。Objective To explore the significance of applying DTI（Diffusion Tensor Imaging） in the diagnosis of cerebral palsy in infants with developmental delays.Methods Thirty-three cases of cerebral palsy infants were selected as the cerebral palsy group,while 33 cases of healthy children as the control group.Then,DTI was performed on both the groups so as to observe the changes of the fiber tracts and research DTI features and its relevance with cerebral palsy.Additionally,the statistical method was applied to compare each FA（Fractional Anisotropy） value in the ROIs（Region-of-Interest） between the cerebral palsy group and the control group.Results Of 33 cerebral palsy infants,sparse and interrupted fiber tracts with abnormal orientation were revealed in different extent in 23 cases on different regions;no obvious changes of fiber tracts were revealed in 10 cases.The FA value in the ROIs of the cerebral palsy group was lower than that of the control group.There were significant differences（P〈0.05） between the two groups.Conclusion Abnormalities revealed by DTI were correlated with cerebral palsy.As an useful method for diagnosis of cerebral palsy in infants and young children with developmental delays,DTI can provide the basis for clinicians to make reasonable treatment plan.

关 键 词：发育迟缓 婴幼儿 脑瘫 磁共振张量成像 各向异性 

分 类 号：R445.2[医药卫生—影像医学与核医学] R742.3[医药卫生—诊断学]