人血白蛋白临床应用1580例调查与分析  

Investigation and analysis on clinical use of human serum albumin in 1 580 patients

作　　者：朱素燕[1] 徐萍[1] 刘瑶[1] 

机构地区：[1]浙江省宁波市第一医院药学部,315010

出　　处：《中国药物与临床》2015年第1期22-25,共4页Chinese Remedies & Clinics

基　　金：浙江省药学会医院药学专项科研基金(2012ZYY26)

摘　　要：目的调查分析宁波地区某三甲综合医院住院患者人血白蛋白的临床应用现状及特点,评价用药合理性。方法回顾性调查该院2012年1月至12月所有使用人血白蛋白的住院患者病历,统计人血白蛋白使用的临床科室分布、用量、用药前白蛋白水平、用药原因等。结果 2012年共有1 580例患者使用过人血白蛋白,总用量为116 379.7 g,平均每人消耗73.66 g,涉及科室为27个,92.59%的患者用药前血清白蛋白的浓度低于30 g/L,用药原因以低蛋白血症占多数(48.86%)。结论该院人血白蛋白的使用存在一定的不合理性,应建立人血白蛋白合理用药评估体系,对临床不合理应用进行干预以提高用药合理性,并呼吁尽快制定基于循证医学的指南。Objective To investigate the current application and characteristics of human serum albumin in hospitalized patients of a 3A grade general hospital in Ningbo, and evaluate the rationality of medication. Methods The medical records of all hospitalized patients given human serum albumin between January and December 2012 were retrospectively investigated. The distribution of clinical department, dosage, human serum albumin level before medication and the reasons of using human serum albumin were statistically analyzed. Results The total dosage in1580 cases given human serum albumin in 2012 was 116 379.7 g with a mean consumption of 73.66 g for each pa-tient, involving 27 departments. The concentration of serum albumin before medication in 92.59% of the patients was under 30 g/L. And the leading cause of albumin use was hypoalbuminemia, found in 48.86% of the patients. Conclusion Certain irrational use of human serum albumin may be present in this hospital. Evaluation system of rational hu-man serum albumin use should be established, and irrational practice should be intervened to improve the rationality of medication. Development of evidence-based guidelines on proper albumin use as soon as possible should be expected.

关 键 词：白蛋白类 药物监测 

分 类 号：R969.3[医药卫生—药理学]