肺泡微石症3例临床分析  

Clinical analysis of pulmonary alveolar microlithiasis in 3 cases

作　　者：赵琪[1] 程京华[2] 丁晶晶[1] 苗立云[1] 蔡后荣[1] 

机构地区：[1]南京大学医学院附属鼓楼医院呼吸科,南京210008 [2]南京军区南京总医院心内科,南京210002

出　　处：《中华实用诊断与治疗杂志》2015年第2期144-145,共2页Journal of Chinese Practical Diagnosis and Therapy

摘　　要：目的总结肺泡微石症的临床表现、影像学表现及组织病理特征。方法回顾性分析3例肺泡微石症患者的临床资料。结果 3例临床均表现为咳嗽,2例伴有胸闷气喘;血常规、肝功能、肾功能、血钙及血磷检测均未见异常;肺功能检查示3例弥散功能降低,2例有限制性通气功能减退;X线胸片均可见弥漫性高密度结节影,中下肺为主;胸部CT检查3例见白描征,2例见火焰征;2例行肺活组织病理检查,示不规则同心层微小结石。结论肺泡微石症临床表现无特异性,影像学表现典型,活检组织病理可明确诊断。Objective To analyze the clinical,radiological and pathological characteristics of pulmonary alveolar microlithiasis（PAM）.Methods The clinical data of three patients with PAM were retrospectively analyzed.Results Three patients were all clinically manifested by cough,in which two patients were complicated with chest tightness and tachypnea.Pulmonary function tests showed decreased lung diffusion capacity in three patients and two of them had restrictive pulmonary hypofunction.Blood routine examination,liver and kidney function,serum calcium and serum phosphorus were normal.The chest X-ray film revealed extensive uniform micronodulation of calcific densities throughout both lungs involving mainly the middle and lower zones,and chest CT showed line drawing in three patients and flame in two.Biopsy of two patients demonstrated microliths with a distinguishing concentric lamellar structure in the lung tissue.Conclusion The clinical manifestation of PAM is not specific,the radiological characteristic of PAM is typical,and the definitive diagnosis requires lung biopsy.

关 键 词：肺泡微石症 影像学 组织病理 

分 类 号：R563.9[医药卫生—呼吸系统]