针灸对比胃肠促动力药治疗功能性消化不良的Meta分析  

The effect of acupuncture and moxibustion on functional dyspepsia compared with prokinetic agents:a meta-analysis

作　　者：吴晓尉[1] 季洪赞[1] 许莲娥[1] 汪芳裕[1] 

机构地区：[1]南京军区南京总医院消化内科,江苏南京210002

出　　处：《中国中西医结合消化杂志》2015年第2期100-104,共5页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

摘　　要：[目的]系统评价针灸对比胃肠促动力药治疗功能性消化不良（FD）的疗效。[方法]通过检索中国知网（CNKI）、中国生物医学文献数据库（CBM）、PubMed、EMBASE、Cochrane Library等数据库,查找有关针灸对比胃肠促动力药治疗FD的随机对照试验,采用Jadad量表行质量评价,应用RevMan5.3软件行Meta分析。[结果]共16个研究包括1 088例FD患者纳入分析。针灸治疗FD的总有效率显著高于胃肠促动力药（RR=1.18,95%CI=1.11～1.24,P〈0.00001）。各项研究均未报道严重不良反应。[结论]针灸用于治疗FD效果优于胃肠促动力药,且安全性较高。由于纳入研究的质量偏低和潜在偏倚,需要高质量、大样本的研究进一步验证结果。[Objective]To systematically compare the effect of acupuncture and moxibustion with prokinetic agents on functional dyspepsia（FD）.[Methods]Databases of China National Knowledge Infrastructure（CNKI）,China Biology Medicine disc（CBM）,PubMed,EMBASE and Cochrane Library were retrieved,and the randomized-controlled trials which compared the effect of acupuncture and moxibustion with prokinetic agents on FD were collected.Jadad quality scale was used for quality assessment.Meta-analysis was performed with RevMan5.3software.[Results]Sixteen studies involving 1 088 FD patients were enrolled.The total effective rate in acupuncture and moxibustion group was significantly higher than that in prokinetic agents group（RR=1.18,95%CI=1.11～1.24,P〈0.00001）.No serious adverse events were reported.[Conclusion]Acupuncture and moxibustion were more effective than prokinetic agents for the treatment of FD with high safety.The findings should be interpreted cautiously due to low quality of included studies and potential biases.

关 键 词：针灸 胃肠促动力药 功能性消化不良 META分析 

分 类 号：R256.3[医药卫生—中医内科学]