飞行人员高血压伴颈动脉粥样硬化形成影响因素的研究  

Study on influencing factors of the hypertension with carotid atherosclerosis in aircrew

作　　者：刘晶[1] 王露今[1] 刘玉华[1] 徐先荣[1] 刘红巾[1] 徐蜀宣[1] 崔丽[1] 付兆君[1] 熊巍[1] 

机构地区：[1]空军总医院全军临床航空医学中心,北京100142

出　　处：《中华航空航天医学杂志》2014年第3期167-170,共4页Chinese Journal of Aerospace Medicine

基　　金：全军“十二五”后勤科研计划面上项目（CKJ11J022）

摘　　要：目的 调查伴颈动脉粥样硬化的高血压飞行人员动态血压参数及心血管危险因素,探讨高血压飞行人员颈动脉粥样硬化形成的影响因素,为防控高血压动脉粥样硬化提供依据. 方法 因高血压住院的53名飞行人员,根据颈部血管超声结果分为高血压（hypertension,HT）无颈动脉粥样硬化组（HT组）,26名;HT合并颈动脉粥样硬化（carotid atherosclerosis,CAS）组（HT＋ CAS组）,27名.对所有入选对象进行病史询问、体检、血生化指标、动态血压检测及比较. 结果 HT＋CAS组的年龄、高血压病程、总胆固醇、甘油三酯及低密度脂蛋白胆固醇水平均大于HT组（t=2.136～4.913,P＜0.05）;动态血压中HT＋ CAS组的夜间平均收缩压（night SBP,nSBP）、24 h脉压差（24 hour pulse pressure,24hPP）、昼间脉压差（day PP,dPP）及夜间脉压差（night PP,nPP）均高于HT组（t=2.154～3.315,P＜0.05）. 结论 年龄、高血压病程、血脂水平、脉压差、夜间收缩压的升高对高血压飞行人员的颈动脉粥样硬化形成有明显促进作用.Objective To study the ambulatory blood pressure （ABPM） and other cardiovascular risk factors in the aircrews with hypertension （HT） complicated carotid atherosclerosis （CAS）,and to find out the evidence for the prevention.Methods Fifty-three hospitalized aircrews were diagnosed by carotid ultrasound examination and then were divided into HT group （n=26） and HT＋CAS group （n=27）.They were inquired case history and received physical and biochemistry examinations,as well as ABPM monitoring for comparison.Results The age,time course of hypertension,levels of total cholesterol,triglyceride,low-density lipoprotein cholesterol of HT＋CAS group were significantly older,longer and higher than those of HT group （t=2.136-4.913,P〈0.05） ; mean systolic pressure at night （nSBP）,24-hour pulse pressure （24 hPP）,day PP （dPP）,night PP （nPP） in ABPM monitoring were different between two groups （t=2.154-3.315,P〈 0.05）.Conclusions Age factor,time course of hypertension,levels of blood fat,PP and nSBP contribute more to cause carotid atherosclerosis in HT aircrew.

关 键 词：高血压 动脉粥样硬化 颈动脉疾病 血压监测 便携式 飞行人员 

分 类 号：R85[医药卫生—航空、航天与航海医学]