神经节苷脂钠注射液治疗对新生儿缺氧缺血性脑病神经行为的影响  

Effects of single hexose ganglioside sialic acid four sodium injection on the neurobehavior of neonatal with hypoxic-ischemic encephalopathy

作　　者：燕民[1] 刘玉田[1] 

机构地区：[1]山东莱芜市人民医院儿科,莱芜271100

出　　处：《中国实用神经疾病杂志》2014年第18期31-33,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的分析神经节苷脂钠注射液治疗对新生儿缺氧缺血性脑病(HIE)神经行为的影响。方法选择我院HIE患者72例,随机分为2组,研究组采用神经节苷脂钠注射液治疗,对照组采用脑蛋白水解物治疗,观察脑CT变化,并采用神经评分(NBNA)进行评价,并对治疗后主要症状及体征恢复时间进行观察分析。结果同对照组相比,研究组临床症状改善明显(P<0.05),主要症状及体征恢复时间显著优于对照组(P<0.05),2组总有效率相比有显著性差异(P<0.05)。结论神经节苷脂钠注射液治疗HIE,在神经行为和症状恢复方面具有较好作用,具有临床重要意义。Objective To investigate the effects of single hexose ganglioside sialic acid four sodium injection on the neurobehavior of neonatal with hypoxic-ischemic encephalopathy（HIE）.Methods 72 neonatal with HIE were randomly divided into the study group（treated with single hexose ganglioside sialic acid four sodium injection）and the control group（treated with brain protein hydrolyzate）.The following indexes of two groups were observed：brain CT,neurological assessment（NBNA）,main symptoms and signs of recovery time after treatment.Results The NBNA scores,total efficiency,main symptoms and signs of recovery time after treatment of neonatal with HIE in the study group were more than these in the control group.Conclusion Single hexose ganglioside sialic acid four sodium injection has better effect on treating the neurobehavior and symptom recovery of neonatal with HIE.

关 键 词：神经节苷脂钠注射液 缺氧缺血性脑病 新生儿 

分 类 号：R722.1[医药卫生—儿科]