正交设计法研究乙酸仲丁酯的合成  

Study on synthesis of sec-butyl acetate by orthogonal design method

作　　者：邓秀琴[1] 高辉[1] 贺小平[1] 

机构地区：[1]辽宁石油化工大学顺华能源学院化学工程系,辽宁抚顺113001

出　　处：《应用化工》2014年第7期1307-1309,共3页Applied Chemical Industry

摘　　要：以NaHSO4·H2O为催化剂,冰乙酸、仲丁醇为原料合成乙酸仲丁酯。利用正交设计法确定了反应的优化条件:催化剂加入量为0.8 g,反应时间为60 min,带水剂加入量为15 mL,醇酸摩尔比为2.5∶1,酯化率可达85%左右。Sec-butyl acetate was synthesized by using NaHSO4 ＆#183;H2 O as catalyst,acetic acid and sec-butyl alcohol as raw materials.The oPtimum conditions were determined by orthogonal design method：add amount of catalyst 0. 8 g,reaction time 60 min,add amount of water-carrying agent 15 mL,molar ratio of sec-butyl alcohol to acetic acid 2. 5：1,the esterification rate could reach 85% or so.

关 键 词：乙酸仲丁酯 合成 NaHSO4·H2O 正交设计 

分 类 号：TQ225.24[化学工程—有机化工]