不同处理方法对鱼金注射液含量影响  

Different processing methods on the content of the Yujin injection

作　　者：肖志强[1] 任哲[1] 杨建刚[1] 郭晨[1] 

机构地区：[1]陕西新药技术开发中心,陕西西安710075

出　　处：《应用化工》2014年第7期1339-1340,共2页Applied Chemical Industry

基　　金：陕西省科技统筹创新工程计划项目(2011KTCG03-03)

摘　　要：建立鱼金注射液含量的气相色谱测定方法,研究鱼金注射液萃取、回流两种处理方式注射液含量变化情况。采用键合交联聚乙二醇为固定液的毛细管柱分离,氢火焰离子化检测器检测,对两种方法提取出的甲基正壬酮进行定量分析。结果表明,鱼金注射液在萃取条件下含量更高、更稳定,确定为鱼金注射液质量标准样品处理方法。To establish a method to detect the content of Yujin injection by gas chromatograPhy,studies the Yujin injection under the extraction method and reflux method for the change of the content. Using bonding crosslinked Polyethylene glycol（ Peg）as the fixed liquid caPillary column seParated,hydrogen flame ionization detector detected the methylnonylketone of the two methods. Result shows that,Yujin in-jection under the condition of extraction content is higher and more stable,determined the extraction method as the standard samPle Processing method for Yujin injection.

关 键 词：气相色谱 甲基正壬酮 萃取 回流 

分 类 号：TQ461[化学工程—制药化工] R917[医药卫生—药物分析学]